Evidence map›Paper›PMID 28409378›Full record

ArticleSurgical endoscopy2017

Percutaneous cholecystostomy: prognostic factors and comparison to cholecystectomy.

Tyler J Loftus, Elisha M Collins, Camille G Dessaigne, Amber N Himmler, Alicia M Mohr, Ryan M Thomas, Charles E Hobson, George A Sarosi, William J Zingarelli

Open access · greenAbstract read
In one paragraph

Article in Surgical endoscopy, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. What is the effect of percutaneous cholesistostomy in patients with acute cholecystitis? when is the right time for the procedure?Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023
    Article
  7. Review
  8. Observational
  9. Article
  10. Review
  11. Review
  12. Cholecystectomy Vs. Cholecystostomy for the Management of Acute Cholecystitis in Elderly Patients.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2019
    Article
  13. Does percutaneous cholecystostomy affect prognosis of patients with acute cholecystitis that are unresponsive to conservative treatment?Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Tyler J LoftusDepartment of Surgery, The University of Florida, Gainesville, FL, USA.ORCID 0000-0001-5354-443X
Elisha M CollinsDepartment of Surgery, The University of Florida, Gainesville, FL, USA.
Camille G DessaigneDepartment of Surgery, The University of Florida, Gainesville, FL, USA.
Amber N HimmlerThe University of Florida College of Medicine, Gainesville, FL, USA.
Alicia M MohrDepartment of Surgery, The University of Florida, Gainesville, FL, USA.
Ryan M ThomasDepartment of Surgery, The University of Florida, Gainesville, FL, USA.
Charles E HobsonThe Malcom Randall Veterans Affairs Medical Center, 1601 SW Archer Road, Gainesville, FL, 32608, USA.
George A SarosiDepartment of Surgery, The University of Florida, Gainesville, FL, USA.
William J ZingarelliDepartment of Surgery, The University of Florida, Gainesville, FL, USA. William.Zingarelli@surgery.ufl.edu.
University of Florida · USMalcom Randall VA Medical Center · US

Funding

PICS: A New Horizon for Surgical Critical CareP50GM111152 · NIGMS · UNIVERSITY OF FLORIDA · PI MOORE, FREDERICK A · 2014 to 2018
$10.7M
Molecular Biology in Burns and TraumaT32GM008721 · NIGMS · UNIVERSITY OF FLORIDA · PI Philip A Efron · 1999 to 2026
$5.0M
Chronic Stress and Anemia Recovery following Major TraumaR01GM105893 · NIGMS · UNIVERSITY OF FLORIDA · PI MOHR, ALICIA M · 2013 to 2021
$3.5M
NIGMS NIH HHS P50 GM111152NIGMS NIH HHS R01 GM105893NIGMS NIH HHS T32 GM008721
6 · The paper itself

Abstract

backgroundData regarding long-term outcomes following percutaneous cholecystostomy (PC) are limited, and comparisons to cholecystectomy (CCY) are lacking. We hypothesized that chronic disease burden would predict 1-year mortality following PC, and that outcomes following PC and CCY would be similar when controlling for preprocedural risk factors.

methodsWe performed a 10-year retrospective cohort analysis of patients with acute cholecystitis managed by PC (n = 114) or CCY (n = 234). Treatment response was assessed by systemic inflammatory response syndrome (SIRS) criteria at PC/CCY and 72 h later. Logistic regression identified predictors of 30-day and 1-year mortality following PC. PC and CCY patients were matched by age, Tokyo Guidelines (TG13) cholecystitis severity grade, and VASQIP calculator predicted mortality (n = 42/group).

resultsThe presence of SIRS at 72 h following PC was associated with 30-day mortality [OR 8.9 (95% CI 2.6-30)]. SIRS at 72 h was present in and 21.4% of all PC patients, significantly higher than unmatched CCY patients (4.7%, p = 0.048). Independent predictors of 1-year mortality following PC were DNR status [19.7 (2.1-186)], disseminated cancer [7.5 (2.1-26)], and congestive heart failure [3.9 (1.4-11)]. PC patients with none of these risk factors had 17.9% 90-day mortality and no deaths after 90 days; late deaths continued to occur among patients with DNR, CHF, or disseminated cancer. At baseline, PC patients had greater acute and chronic disease burden than CCY patients. After matching, PC and CCY patients had similar age (69 vs. 70 years), TG13 grade (2.4 vs. 2.4), and predicted 30-day mortality (5.5 vs. 6.8%). Matched PC patients had higher 30-day mortality (14.3 vs. 2.4%, p = 0.109) and 180-day mortality (28.6 vs. 7.1%, p = 0.048).

conclusionsTreatment response to PC predicted 30-day mortality; DNR status, and chronic diseases predicted 1-year mortality. Although the matching procedure did not eliminate selection bias, PC was associated with persistent systemic inflammation and higher long-term mortality than CCY.

Indexed as

AdultAgedCholecystectomyCholecystitis, AcuteCholecystostomyCohort StudiesCost of IllnessFemaleHumansMaleMiddle AgedPrognosisRetrospective StudiesRisk FactorsSurvival AnalysisSystemic Inflammatory Response SyndromeCholecystectomyCholecystitisMortalityOutcomesPercutaneous cholecystostomyPrognosis

Identifiers

PMID28409378
PMCPMC5733717
OpenAlexW2606561372

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.