Evidence map›Paper›PMID 28409339›Full record

ArticleMolecular imaging and biology2017

Quantification of Tumor Hypoxic Fractions Using Positron Emission Tomography with [

Olivia J Kelada, Sara Rockwell, Ming-Qiang Zheng, Yiyun Huang, Yanfeng Liu, Carmen J Booth, Roy H Decker, Uwe Oelfke, Richard E Carson, David J Carlson

Open access · greenAbstract read
In one paragraph

Article in Molecular imaging and biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Trial
  2. Article
  3. [Cancers · 2023
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Longitudinal PET imaging of tumor hypoxia during the course of radiotherapy.European journal of nuclear medicine and molecular imaging · 2018
    Review
  14. Intracellular hypoxia measured byBreast cancer research : BCR · 2018
    Observational
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Olivia J KeladaDepartment of Therapeutic Radiology, Yale University School of Medicine, P.O. Box 208040, New Haven, CT, 06520-8040, USA.
Sara RockwellDepartment of Therapeutic Radiology, Yale University School of Medicine, P.O. Box 208040, New Haven, CT, 06520-8040, USA.
Ming-Qiang ZhengDepartment of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA.
Yiyun HuangDepartment of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA.
Yanfeng LiuDepartment of Therapeutic Radiology, Yale University School of Medicine, P.O. Box 208040, New Haven, CT, 06520-8040, USA.
Carmen J BoothSection of Comparative Medicine, Yale University School of Medicine, New Haven, CT, USA.
Roy H DeckerDepartment of Therapeutic Radiology, Yale University School of Medicine, P.O. Box 208040, New Haven, CT, 06520-8040, USA.
Uwe OelfkeDepartment of Medical Physics in Radiation Oncology, German Cancer Research Center, Heidelberg, Germany.
Richard E CarsonDepartment of Diagnostic Radiology, Yale University School of Medicine, New Haven, CT, USA.
David J CarlsonDepartment of Therapeutic Radiology, Yale University School of Medicine, P.O. Box 208040, New Haven, CT, 06520-8040, USA. david.j.carlson@yale.edu.
Yale University · USHeidelberg University · DE

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Yale Pathology Tissue Services Shared ResourceP30CA016359 · NCI · YALE UNIVERSITY · PI MEGAN C KING · 1985 to 2026
$85.0M
NCATS NIH HHS UL1 TR001863NCI NIH HHS P30 CA016359
6 · The paper itself

Abstract

purposeThe purpose of this study is to use dynamic [ PROCEDURES: BALB/c mice with EMT6 subcutaneous tumors were selected for PET imaging and invasive pO

resultsHFs defined by TBR (≥1.2, ≥1.3, and ≥1.4) ranged from 2 to 85 % of absolute tumor volume. HFs defined by K

conclusions[

Indexed as

Positron-Emission TomographyAnimalsCell HypoxiaCell Line, TumorHumansKineticsMaleMice, Inbred BALB CMisonidazoleMusclesNeoplasmsOxygenTomography, X-Ray ComputedTumor BurdenfluoromisonidazoleMisonidazoleOxygen[18F]FMISOHypoxiaPetpO2 electrodeQuantificationTumor

Identifiers

PMID28409339
PMCPMC5640490
OpenAlexW2605400086

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.