SynthesisInternational archives of occupational and environmental health2017
Occupational exposure to respirable crystalline silica and chronic non-malignant renal disease: systematic review and meta-analysis.
Synthesis in International archives of occupational and environmental health, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.
- Risk Assessment of Silicosis and Lung Cancer Mortality associated with Occupational Exposure to Crystalline Silica in Iran.Journal of research in health sciences · 2022Pooled it
- Integrated pathological and molecular characterisation of respiratory disease in extensively reared Sicilian Black pigs: detection of Mycoplasma hyopneumoniae, porcine circovirus type 2, and concurrent pulmonary silicosis.Veterinary research communications · 2026Article
- Association between job characteristics and kidney function among men: a cross-sectional analysis of the Rafsanjan cohort study.BMC nephrology · 2025Article
- A review of silicosis and other silica-related diseases in the engineered stone countertop processing industry.Journal of occupational medicine and toxicology (London, England) · 2025Review
- Occupational exposure to respirable and inhalable dust and its components in a Nicaraguan sugarcane plantation.Occupational and environmental medicine · 2025Article
- Impact of Respiratory Dust on Health: A Comparison Based on the Toxicity of PM2.5, Silica, and Nanosilica.International journal of molecular sciences · 2024Review
- Occupational particle exposure and chronic kidney disease: a cohort study in Swedish construction workers.Occupational and environmental medicine · 2024Article
- Article
- Secondary prevention of silicosis and silico-tuberculosis by periodic screening of silica dust exposed workers using serum club cell protein 16 as a proxy marker.Health science reports · 2021Article
- Silicosis, progressive massive fibrosis and silico-tuberculosis among workers with occupational exposure to silica dusts in sandstone mines of Rajasthan state: An urgent need for initiating national silicosis control programme in India.Journal of family medicine and primary care · 2021Article
- Demonstration of Subclinical Early Nephrotoxicity Induced by Occupational Exposure to Silica among Workers in Pottery Industry.The international journal of occupational and environmental medicine · 2020Article
- Respiratory Symptoms and Diminished Lung Functions Associated with Occupational Dust Exposure Among Iron Ore Mine Workers in Iran.The open respiratory medicine journal · 2020Article
- Caplan's Syndrome with a twist.International journal of clinical case reports and reviews : open access · 2020Article
- Clinical, Paraclinical, and Evolutionary Profiles of Kidney Failure in Gold Miners Hospitalized in a Nephrological Service in a Sub-Saharan African Country.International journal of nephrology · 2020Article
- Renal involvement in a silicosis patient - case report and literature review.Renal failure · 2019Review
- Fossil Shell Flour in Livestock Production: A Review.Animals : an open access journal from MDPI · 2019Review
- Particulate Matter (Fine Particle) and Urologic Diseases.International neurourology journal · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhile occupational exposure to respirable silica is known to lead to lung disease, most notably silicosis, its association with chronic kidney disease is unclear.
objectivesThis review explores the association between occupational exposure to respirable silica and chronic non-malignant renal disease such as glomerulonephritis. The evidence has been collected and compiled. Possible sources of bias are thoroughly discussed.
methodsCohort studies with silica exposure and case-control studies of renal disease were searched in PubMed until January 2015. Two authors independently abstracted data; any disagreement was resolved by consulting a third reviewer. A meta-analysis was performed to evaluate the association to silica exposure.
resultsA total of 23 cohort and four case-control studies were included in the analysis. The meta-analysis of cohort studies yielded elevated overall SMRs for renal disease. Some studies, however, included dose-response analyses, most of which did not show a positive trend. The approaches and results of the case-control studies were very heterogeneous.
conclusionsWhile the studies of cohorts exposed to silica found elevated SMRs for renal disease, no clear evidence of a dose-response relationship emerged. The elevated risk may be attributed to diagnostic and methodological issues. In order to permit a reliable estimation of a possible causal link, exposed cohorts should be monitored for renal disease, as the information from mortality studies is hardly reliable in this field.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.