ArticleRevista brasileira de ortopedia
Malignant transformation in chronic osteomyelitis.
Article in Revista brasileira de ortopedia. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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10 citing papers in PubMed, 18 citations in OpenAlex.
- Squamous Cell Carcinoma Arising from Chronic Osteomyelitis: A Single-Center Case Series of Six Patients.Infection and drug resistance · 2026Article
- Texture analysis using short-tau inversion recovery magnetic resonance images to differentiate squamous cell carcinoma of the gingiva from medication-related osteonecrosis of the jaw.Oral radiology · 2024Article
- Management of Squamous Cell Carcinoma in Chronic Osteomyelitis: Our Experience, Review of the Literature and Role of MRI in Differential Diagnosis.Diagnostics (Basel, Switzerland) · 2022Article
- Chondroblastic Osteosarcoma Associated with Previous Chronic Osteomyelitis Caused byVeterinary sciences · 2022Article
- Squamous Cell Carcinoma Arising from Chronic Osteomyelitis in the Extremities: Treatment Approach and Oncological Outcomes-A Systematic Review of the Literature.Journal of skin cancer · 2022Review
- Clinical characteristics, treatment, and prognosis of squamous cell carcinoma arising from extremity chronic osteomyelitis: a synthesis analysis of one hundred and seventy six reported cases.International orthopaedics · 2020Article
- [Squamous cell carcinoma in a patient with chronic osteomyelitic lesion: a case report].The Pan African medical journal · 2020Article
- [Comparative study of different concentrations of methicillin-resistantZhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2018Article
- [Malignant transformation of chronic osteomyelitis: a case report].The Pan African medical journal · 2017Article
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3 authors at 1 institution in 1 country.
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Abstract
introductionCarcinomatous degeneration is a rare and late complication developing decades after the diagnosis of chronic osteomyelitis.
objectivesTo present the results from a retrospective study of six cases of squamous cell carcinoma arising from chronic osteomyelitis.
methodsSix cases of chronic osteomyelitis related to cutaneous squamous cell carcinoma were identified. The cause and characteristics of the osteomyelitis were analyzed, as well as time up to malignancy, the suspicion signs for malignancy, the localization and histological type of the cancer, and the type and result of the treatment.
resultsThe mean time between osteomyelitis onset and the diagnosis of malignant degeneration was 49.17 years (range: 32-65). The carcinoma resulted from tibia osteomyelitis in five cases and from femur osteomyelitis in one. The pathological examination indicated cutaneous squamous cell carcinoma in all cases. All the patients were staged as N0M0, except for one, whose lomboaortic lymph nodes were affected. The treatment consisted of amputation proximal to the tumor in all patients. No patient presented signs of local recurrence and only one had carcinoma metastasis.
conclusionEarly diagnosis and proximal amputation are essential for prognosis and final results in carcinomatous degeneration secondary to chronic osteomyelitis.
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