ReviewF1000Research2017
X chromosome inactivation: new players in the initiation of gene silencing.
Review in F1000Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Genomic Instability and Clonal Hematopoiesis in the Deep-Space Environment: The Role of Sex-Chromosome Asymmetry and High-LET Radiation.Current stem cell reports · 2026Article
- A previously unreportedDigital journal of ophthalmology : DJO · 2025Article
- Revisiting the consequences of deleting the X inactivation center.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- The nuclear functions of long noncoding RNAs come into focus.Non-coding RNA research · 2021Review
- Attrition of X Chromosome Inactivation in Aged Hematopoietic Stem Cells.Stem cell reports · 2021Article
- Biological Function of Long Non-coding RNA (LncRNA) Xist.Frontiers in cell and developmental biology · 2021Review
- Trans- and cis-acting effects of Firre on epigenetic features of the inactive X chromosome.Nature communications · 2020Article
- Architectural RNA in chromatin organization.Biochemical Society transactions · 2020Review
- Paradoxical Effects of a Cytokine and an Anticonvulsant Strengthen the Epigenetic/Enzymatic Avenue for Autism Research.Frontiers in cellular neuroscience · 2020Article
- Nonendocrine mechanisms of sex bias in rheumatic diseases.Nature reviews. Rheumatology · 2019Review
- ImmGen report: sexual dimorphism in the immune system transcriptome.Nature communications · 2019Article
- The role of transcription in shaping the spatial organization of the genome.Nature reviews. Molecular cell biology · 2019Review
- Recent Advances in Understanding the Reversal of Gene Silencing During X Chromosome Reactivation.Frontiers in cell and developmental biology · 2019Review
- Extensive cellular heterogeneity of X inactivation revealed by single-cell allele-specific expression in human fibroblasts.Proceedings of the National Academy of Sciences of the United States of America · 2018Article
- The genetic basis of disease.Essays in biochemistry · 2018Review
- Effects of human sex chromosome dosage on spatial chromosome organization.Molecular biology of the cell · 2018Article
- Changes in the position and volume of inactive X chromosomes during the G0/G1 transition.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2018Article
- Development and application of an integrated allele-specific pipeline for methylomic and epigenomic analysis (MEA).BMC genomics · 2018Article
- The transcriptional profiles and functional implications of long non-coding RNAs in the unfolded protein response.Scientific reports · 2018Article
- Trichloroethylene-induced alterations in DNA methylation were enriched in polycomb protein binding sites in effector/memory CD4Environmental epigenetics · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
X chromosome inactivation (XCI) is a dosage compensation process that was adopted by female mammals to balance gene dosage between XX females and XY males. XCI starts with the upregulation of the non-coding RNA Xist, after which most X-linked genes are silenced and acquire a repressive chromatin state. Even though the chromatin marks of the inactive X have been fairly well described, the mechanisms responsible for the initiation of XCI remain largely unknown. In this review, we discuss recent developments that revealed unexpected factors playing a role in XCI and that might be of crucial importance to understand the mechanisms responsible for the very first steps of this chromosome-wide gene-silencing event.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.