Evidence map›Paper›PMID 28408966›Full record

ArticleThe annals of applied statistics2017

Gene Network Reconstruction using Global-Local Shrinkage Priors.

Gwenaël G R Leday, Mathisca C M de Gunst, Gino B Kpogbezan, Aad W van der Vaart, Wessel N van Wieringen, Mark A van de Wiel

Abstract read
In one paragraph

Article in The annals of applied statistics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  4. Semi-supervised empirical Bayes group-regularized factor regression.Biometrical journal. Biometrische Zeitschrift · 2022
    Article
  5. Article
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  12. Learning from a lot: Empirical Bayes for high-dimensional model-based prediction.Scandinavian journal of statistics, theory and applications · 2019
    Article
  13. An empirical Bayes approach to network recovery using external knowledge.Biometrical journal. Biometrische Zeitschrift · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Gwenaël G R LedayMRC Biostatistics Unit, Cambridge Institute of Public Health, Forvie Site, Robinson Way, Cambridge Biomedical Campus, Cambridge CB2 0SR, United Kingdom.
Mathisca C M de GunstVrije Universiteit Amsterdam, Department of Mathematics, Vrije Universiteit Amsterdam, De Boelelaan 1081, 1081 HV Amsterdam, The Netherlands.
Gino B KpogbezanLeiden University, Mathematical Institute, Faculty of Science, Leiden University, P.O. Box 9512, 2300 RA Leiden, The Netherlands.
Aad W van der VaartVU University Medical Center, Department of Epidemiology and Biostatistics, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands.
Wessel N van WieringenVrije Universiteit Amsterdam, Department of Mathematics, Vrije Universiteit Amsterdam, De Boelelaan 1081, 1081 HV Amsterdam, The Netherlands.
Mark A van de WielVrije Universiteit Amsterdam, Department of Mathematics, Vrije Universiteit Amsterdam, De Boelelaan 1081, 1081 HV Amsterdam, The Netherlands.

Funding

Medical Research Council MC_UP_0801/1Medical Research Council MC_UU_00002/10
6 · The paper itself

Abstract

Reconstructing a gene network from high-throughput molecular data is an important but challenging task, as the number of parameters to estimate easily is much larger than the sample size. A conventional remedy is to regularize or penalize the model likelihood. In network models, this is often done

Indexed as

Bayesian inferenceEmpirical BayesShrinkageUndirected gene networkVariational approximation

Identifiers

PMID28408966
PMCPMC5388190

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.