ArticleNeuropsychiatric disease and treatment2017
An Internet-based program for depressive symptoms using human and automated support: a randomized controlled trial.
Article in Neuropsychiatric disease and treatment, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 4 registered trials, which are not on this map. Cited by 48 papers, 8 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Internet-based Depression Treatment. Differential Efficacy of Different Specific Therapeutic Components: Behavioral Activation and Positive Psychology.
Cultural Adaptation of the Smile is Fun Program for the Treatment of Depression in the Ecuadorian Public Health Care System: A Study Protocol for a Randomized Controlled Trial
Implementation of a Psychological Online Intervention for Low to Moderate Depression in Primary Health Care: a Study Protocol
Telephone Support vs. Self-guidance in an Internet-based Self-administered Psychological Program for the Treatment of Depression
Who cites it
48 citing papers in PubMed, 8 syntheses or guidelines pooled it.
- Heterogeneity of Treatment Effects in Internet- and Mobile-Based Interventions for Depression: A Systematic Review and Meta-Analysis.JAMA network open · 2024Pooled it
- Time-Dependent Changes in Depressive Symptoms Among Control Participants in Digital-Based Psychological Intervention Studies: Meta-analysis of Randomized Controlled Trials.Journal of medical Internet research · 2023Pooled it
- Characteristics of Mobile Health Platforms for Depression and Anxiety: Content Analysis Through a Systematic Review of the Literature and Systematic Search of Two App Stores.Journal of medical Internet research · 2022Pooled it
- Exploring the Role of Persuasive Design in Unguided Internet-Delivered Cognitive Behavioral Therapy for Depression and Anxiety Among Adults: Systematic Review, Meta-analysis, and Meta-regression.Journal of medical Internet research · 2021Pooled it
- Internet-Based Cognitive Behavioral Therapy for Depression: A Systematic Review and Individual Patient Data Network Meta-analysis.JAMA psychiatry · 2021Pooled it
- Effect of Engagement With Digital Interventions on Mental Health Outcomes: A Systematic Review and Meta-Analysis.Frontiers in digital health · 2021Pooled it
- Adherence Reporting in Randomized Controlled Trials Examining Manualized Multisession Online Interventions: Systematic Review of Practices and Proposal for Reporting Standards.Journal of medical Internet research · 2019Pooled it
- Is self-guided internet-based cognitive behavioural therapy (iCBT) harmful? An individual participant data meta-analysis.Psychological medicine · 2018Pooled it
- An Unguided, Computerized Cognitive Behavioral Therapy Intervention (TreadWill) in a Lower Middle-Income Country: Pragmatic Randomized Controlled Trial.Journal of medical Internet research · 2023Trial
- Negative and Positive Affect Regulation in a Transdiagnostic Internet-Based Protocol for Emotional Disorders: Randomized Controlled Trial.Journal of medical Internet research · 2021Trial
- Effectiveness of a Transdiagnostic Guided Internet-Delivered Protocol for Emotional Disorders Versus Treatment as Usual in Specialized Care: Randomized Controlled Trial.Journal of medical Internet research · 2020Trial
- Use of a Fully Automated Internet-Based Cognitive Behavior Therapy Intervention in a Community Population of Adults With Depression Symptoms: Randomized Controlled Trial.Journal of medical Internet research · 2019Trial
- Efficacy of an internet-based exposure treatment for flying phobia (NO-FEAR Airlines) with and without therapist guidance: a randomized controlled trial.BMC psychiatry · 2019Trial
- Gentle Mind-A Podcast on Self-Compassion and Character Strengths to Enhance Well-Being in University Students: A Controlled Feasibility Study.Behavioral sciences (Basel, Switzerland) · 2026Article
- Application of the Supportive Accountability Model in Digital Health Interventions: Scoping Review.Journal of medical Internet research · 2025Article
- Is one additional phone call enough? - Effectiveness of additional human support to reduce dropout from an internet-based intervention for depressive symptoms: A randomized-controlled trial.Internet interventions · 2025Article
- Does human support add value to persuasive design-based digital mental health interventions? A propensity score matching study of a digital parenting program.Frontiers in digital health · 2025Article
- A scoping review of therapist behaviors in guided digital mental health interventions.Internet interventions · 2024Article
- Telephone support vs. self-guidance in an Internet-based self-administered psychological program for the treatment of depression: Protocol for a hybrid type 1 effectiveness-implementation randomized controlled trial.Internet interventions · 2024Article
- A systematic review on automated clinical depression diagnosis.Npj mental health research · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to analyze the efficacy of an Internet-based program for depressive symptoms using automated support by information and communication technologies (ICTs) and human support. PATIENTS AND
methodsAn Internet-based program was used to teach adaptive ways to cope with depressive symptoms and daily problems. A total of 124 participants who were experiencing at least one stressful event that caused interference in their lives, many of whom had clinically significant depressive symptoms, were randomly assigned into either an intervention group with ICT support (automated mobile phone messages, automated emails, and continued feedback through the program); an intervention group with ICT support plus human support (brief weekly support phone call without clinical content); or a waiting-list control. At pre-, post-, and 12-month follow-up, they completed depression, anxiety, positive and negative effect, and perceived stress measures. Results were analyzed using both intention-to-treat and completers data. The majority were women (67.7%), with a mean age of 35.6 years (standard deviation =9.7).
resultsThe analysis showed that the two intervention groups improved significantly pre- to posttreatment, compared with the control group. Furthermore, improvements were maintained at the 12-month follow-up. Adherence and satisfaction with the program was high in both conditions.
conclusionThe Internet-based program was effective and well accepted, with and without human support, showing that ICT-based automated support may be useful. It is essential to continue to study other ICT strategies for providing support.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.