Evidence map›Paper›PMID 28408825›Full record

ArticleInternational journal of nanomedicine2017

A tetraethylene glycol coat gives gold nanoparticles long in vivo half-lives with minimal increase in size.

Julian Ds Willett, Marlon G Lawrence, Jennifer C Wilder, Oliver Smithies

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of nanomedicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 98% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Julian Ds WillettDepartment of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Marlon G LawrenceDepartment of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Jennifer C WilderDepartment of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Oliver SmithiesDepartment of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · US

Funding

MODELS FOR STUDYING THE GENETICS OF HYPERTENSIONR01HL049277 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MAEDA, NOBUYO · 1992 to 2025
$17.5M
Renal Processing of AlbuminR21DK080302 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SMITHIES, OLIVER · 2009 to 2010
$407k
NHLBI NIH HHS R01 HL049277NIDDK NIH HHS R21 DK080302
6 · The paper itself

Abstract

In this study, we describe the experiments determining whether coating gold nanoparticles with tetraethylene glycol (TEG) provides pharmacologically relevant advantages, such as increased serum half-life and resistance to protein adsorption. Monodisperse TEG-coated, NaBH

Indexed as

AnimalsFemaleGoldHalf-LifeKidneyMiceMice, Inbred StrainsMicroscopy, Electron, TransmissionNanoparticlesParticle SizePolyethylene GlycolsSpleenTissue DistributionGoldPolyethylene Glycolstetraethylene glycolkidney clearancepolyethylene glycolspleen clearancesplenectomytetraethylene glycoltetraethylene glycol coating

Identifiers

PMID28408825
PMCPMC5383068
OpenAlexW2603416408

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.