Evidence map›Paper›PMID 28408709›Full record

SynthesisCirculation. Cardiovascular genetics2017

Heritability of the Severity of the Metabolic Syndrome in Whites and Blacks in 3 Large Cohorts.

Solomon K Musani, Lisa J Martin, Jessica G Woo, Michael Olivier, Matthew J Gurka, Mark D DeBoer

Erratum issuedOpen access · diamondAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Circulation. Cardiovascular genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Solomon K MusaniFrom the Jackson Heart Study, University of Mississippi Medical Center, Jackson (S.K.M.); Division of Human Genetics (L.J.M.) and Division of Epidemiology & Biostatistics (J.G.W.), Cincinnati Children's Hospital Medical Center, OH; Department of Pediatrics, University of Cincinnati, OH (L.J.M., J.G.W.); Texas Biomedical Research Institute, San Antonio (M.O.); Department of Health Outcomes & Policy, University of Florida, Gainesville (M.J.G.); and Department of Pediatrics, University of Virginia, Charlottesville (M.D.D.).
Lisa J MartinFrom the Jackson Heart Study, University of Mississippi Medical Center, Jackson (S.K.M.); Division of Human Genetics (L.J.M.) and Division of Epidemiology & Biostatistics (J.G.W.), Cincinnati Children's Hospital Medical Center, OH; Department of Pediatrics, University of Cincinnati, OH (L.J.M., J.G.W.); Texas Biomedical Research Institute, San Antonio (M.O.); Department of Health Outcomes & Policy, University of Florida, Gainesville (M.J.G.); and Department of Pediatrics, University of Virginia, Charlottesville (M.D.D.).
Jessica G WooFrom the Jackson Heart Study, University of Mississippi Medical Center, Jackson (S.K.M.); Division of Human Genetics (L.J.M.) and Division of Epidemiology & Biostatistics (J.G.W.), Cincinnati Children's Hospital Medical Center, OH; Department of Pediatrics, University of Cincinnati, OH (L.J.M., J.G.W.); Texas Biomedical Research Institute, San Antonio (M.O.); Department of Health Outcomes & Policy, University of Florida, Gainesville (M.J.G.); and Department of Pediatrics, University of Virginia, Charlottesville (M.D.D.).
Michael OlivierFrom the Jackson Heart Study, University of Mississippi Medical Center, Jackson (S.K.M.); Division of Human Genetics (L.J.M.) and Division of Epidemiology & Biostatistics (J.G.W.), Cincinnati Children's Hospital Medical Center, OH; Department of Pediatrics, University of Cincinnati, OH (L.J.M., J.G.W.); Texas Biomedical Research Institute, San Antonio (M.O.); Department of Health Outcomes & Policy, University of Florida, Gainesville (M.J.G.); and Department of Pediatrics, University of Virginia, Charlottesville (M.D.D.).
Matthew J GurkaFrom the Jackson Heart Study, University of Mississippi Medical Center, Jackson (S.K.M.); Division of Human Genetics (L.J.M.) and Division of Epidemiology & Biostatistics (J.G.W.), Cincinnati Children's Hospital Medical Center, OH; Department of Pediatrics, University of Cincinnati, OH (L.J.M., J.G.W.); Texas Biomedical Research Institute, San Antonio (M.O.); Department of Health Outcomes & Policy, University of Florida, Gainesville (M.J.G.); and Department of Pediatrics, University of Virginia, Charlottesville (M.D.D.).
Mark D DeBoerFrom the Jackson Heart Study, University of Mississippi Medical Center, Jackson (S.K.M.); Division of Human Genetics (L.J.M.) and Division of Epidemiology & Biostatistics (J.G.W.), Cincinnati Children's Hospital Medical Center, OH; Department of Pediatrics, University of Cincinnati, OH (L.J.M., J.G.W.); Texas Biomedical Research Institute, San Antonio (M.O.); Department of Health Outcomes & Policy, University of Florida, Gainesville (M.J.G.); and Department of Pediatrics, University of Virginia, Charlottesville (M.D.D.). deboer@virginia.edu.
University of Cincinnati · USTexas Biomedical Research Institute · USUniversity of Florida Health · US

Funding

SOLAR-Eclipse Computational Tools for Imaging GeneticsR01EB015611 · NIBIB · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI KOCHUNOV, PETER V. · 2012 to 2024
$5.0M
Socioeconomic Status and Subjective Social Status as Modifiers of Stressors and Discrimination in their Relationship with MetS Severity Over TimeR01HL120960 · NHLBI · WEST VIRGINIA UNIVERSITY · PI DEBOER, MARK DANIEL, GURKA, MATTHEW JAMES · 2014 to 2018
$2.1M
NHLBI NIH HHS HHSN268201300046CNHLBI NIH HHS HHSN268201300047CNHLBI NIH HHS HHSN268201300048CNHLBI NIH HHS HHSN268201300049CNHLBI NIH HHS HHSN268201300050CNHLBI NIH HHS R01 HL120960
6 · The paper itself

Abstract

backgroundAlthough dichotomous criteria for the metabolic syndrome (MetS) appear heritable, it is not known whether MetS severity as assessed by a continuous MetS score is heritable and whether this varies by race. METHODS AND

resultsWe used SOLAR (Sequential Oligogenic Linkage Analysis Routines) to evaluate heritability of Adult Treatment Panel-III MetS and a sex- and race-specific MetS severity

conclusionsMetS severity seems highly heritable among whites and blacks. This continuous MetS severity

Indexed as

AdultAgedBlack PeopleBlood GlucoseBlood PressureCohort StudiesFemaleGenotypeHumansLipoproteins, HDLMaleMetabolic SyndromeMiddle AgedPhenotypeSeverity of Illness IndexTriglyceridesBlood GlucoseLipoproteins, HDLTriglyceridesadultcardiovascular diseasefastinggeneticsglucose

Identifiers

PMID28408709
PMCPMC5481724
OpenAlexW2977902871

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.