Evidence map›Paper›PMID 28408636›Full record

ArticlePhysiological reports2017

Aldosterone regulates a 5' variant sgk1 transcript via a shared hormone response element in the sgk1 5' regulatory region.

Nandita S Raikwar, Christie P Thomas

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Physiological reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 97% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Nandita S RaikwarDepartment of Internal Medicine, University of Iowa College of Medicine, Iowa City, Iowa.
Christie P ThomasDepartment of Internal Medicine, University of Iowa College of Medicine, Iowa City, Iowa christie-thomas@uiowa.edu.
University of Iowa · USVeterans Health Administration · US

Funding

Expression of sFlt1 and its function in the glomerular endotheliumR01DK090053 · NIDDK · UNIVERSITY OF IOWA · PI THOMAS, CHRISTIE P. · 2010 to 2014
$1.6M
Sgk1 in Na+ transport in fetal lung epitheliaR01HL071664 · NHLBI · UNIVERSITY OF IOWA · PI THOMAS, CHRISTIE P. · 2003 to 2007
$1.4M
NHLBI NIH HHS R01 HL071664NIDDK NIH HHS R01 DK090053
6 · The paper itself

Abstract

We previously identified a 5' variant alternate transcript of Sgk1 (Sgk1_v3) encoding an NH

Indexed as

Response Elements5' Flanking RegionAldosteroneAnimalsCell Line, TumorGlucocorticoidsHEK293 CellsHumansImmediate-Early ProteinsMiceMice, Inbred C57BLNephronsPotassiumProtein Serine-Threonine KinasesRespiratory MucosaRNA, MessengerAldosteroneGlucocorticoidsImmediate-Early ProteinsPotassiumProtein Serine-Threonine KinasesRNA, MessengerSerum-Glucocorticoid Regulated KinasesSodiumAldosteroneepithelial Na+ channelNa+ transport

Identifiers

PMID28408636
PMCPMC5392512
OpenAlexW2605539753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.