ArticleScience (New York, N.Y.)2017
Nanoscale-length control of the flagellar driveshaft requires hitting the tethered outer membrane.
Article in Science (New York, N.Y.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
55 citing papers in PubMed.
- A periplasmic layer formed by an outer membrane lipoprotein governs the cell-envelope integrity and stiffness of Leptospira interrogans.Communications biology · 2026Article
- Active removal of inhibitory components drives the flagellar Type III Secretion Specificity Switch.bioRxiv : the preprint server for biology · 2026Article
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- Peptidoglycan-outer membrane attachment generates periplasmic pressure to prevent lysis in Gram-negative bacteria.Nature microbiology · 2025Article
- An inner membrane protein is covalently attached to peptidoglycan in the γ-proteobacterium Dickeya dadantii.Communications biology · 2025Article
- β-Barrel proteins dictate the effect of core oligosaccharide composition on outer membrane mechanics.Biophysical journal · 2025Article
- Evolution of a large periplasmic disk in Campylobacterota flagella enables both efficient motility and autoagglutination.Developmental cell · 2024Article
- β-barrel proteins dictate the effect of core oligosaccharide composition on outer membrane mechanics.bioRxiv : the preprint server for biology · 2024Article
- FlhE functions as a chaperone to prevent formation of periplasmic flagella in Gram-negative bacteria.Nature communications · 2024Article
- The TAM, a Translocation and Assembly Module for protein assembly and potential conduit for phospholipid transfer.EMBO reports · 2024Review
- Surveying membrane landscapes: a new look at the bacterial cell surface.Nature reviews. Microbiology · 2023Review
- Design and Motion Analysis of a Soft-Limb Robot Inspired by Bacterial Flagella.Biomimetics (Basel, Switzerland) · 2023Article
- Identification and characterization of an abundant lipoprotein from Methylacidiphilum fumariolicum SolV.Archives of microbiology · 2023Article
- Collective transport and reconfigurable assembly of nematic colloids by light-driven cooperative molecular reorientations.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Envelope-Stress Sensing Mechanism of Rcs and Cpx Signaling Pathways in Gram-Negative Bacteria.Journal of microbiology (Seoul, Korea) · 2023Review
- Salmonella Subpopulations Identified from Human Specimens Express Heterogenous Phenotypes That Are Relevant to Clinical Diagnosis.Microbiology spectrum · 2023Article
- Type III Secretion System Repressor RhpR Induces GrlP, a Glycine-Rich Outer Membrane Lipoprotein with Functions in Regulating the Periplasmic Space and Pleiotropic Responses.Applied and environmental microbiology · 2023Article
- In situ visualization of Braun's lipoprotein onScience advances · 2023Article
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Corrections and comments
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Authors and funding
5 authors.
Funding
Abstract
The bacterial flagellum exemplifies a system where even small deviations from the highly regulated flagellar assembly process can abolish motility and cause negative physiological outcomes. Consequently, bacteria have evolved elegant and robust regulatory mechanisms to ensure that flagellar morphogenesis follows a defined path, with each component self-assembling to predetermined dimensions. The flagellar rod acts as a driveshaft to transmit torque from the cytoplasmic rotor to the external filament. The rod self-assembles to a defined length of ~25 nanometers. Here, we provide evidence that rod length is limited by the width of the periplasmic space between the inner and outer membranes. The length of Braun's lipoprotein determines periplasmic width by tethering the outer membrane to the peptidoglycan layer.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.