Evidence map›Paper›PMID 28408528›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2017

Cerenkov Radiation-Induced Photoimmunotherapy with

Yuko Nakamura, Tadanobu Nagaya, Kazuhide Sato, Shuhei Okuyama, Fusa Ogata, Karen Wong, Stephen Adler, Peter L Choyke, Hisataka Kobayashi

Abstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Influence of Different Parameters on the Labeling Efficiency of Technetium-99m Radiopharmaceuticals: Kuwait Nuclear Medicine Departments Experiences.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Effect of Cerenkov Radiation-Induced Photodynamic Therapy withInternational journal of molecular sciences · 2021
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yuko NakamuraMolecular Imaging Program, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland; and.
Tadanobu NagayaMolecular Imaging Program, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland; and.
Kazuhide SatoMolecular Imaging Program, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland; and.
Shuhei OkuyamaMolecular Imaging Program, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland; and.
Fusa OgataMolecular Imaging Program, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland; and.
Karen WongMolecular Imaging Program, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland; and.
Stephen AdlerClinical Research Directorate/Clinical Monitoring Research Program, Leidos Biomedical Research, Inc., National Cancer Institute Campus at Frederick, Frederick, Maryland.
Peter L ChoykeMolecular Imaging Program, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland; and.
Hisataka KobayashiMolecular Imaging Program, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland; and kobayash@mail.nih.gov.

Funding

Growth Factor Imaging and PhotoimmunotherapyZIABC010656 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI CHOYKE, PETER L · 2009 to 2024
$31.6M
Cancer-cell specific therapy: photo-immunotherapyZIABC011513 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI KOBAYASHI, HISATAKA · 2013 to 2025
$15.5M
6 · The paper itself

Abstract

Near-infrared photoimmunotherapy (NIR-PIT) is a new cancer treatment that combines the specificity of antibodies for targeting tumors with toxicity induced by photoabsorbers after irradiation with NIR light. A limitation of NIR-PIT is the inability to deliver NIR light to a tumor located deep inside the body. Cerenkov radiation (CR) is the ultraviolet and blue light that is produced by a charged particle traveling through a dielectric medium faster than the speed of light in that medium and is commonly produced during radioactive decay. Here, we demonstrate the feasibility of using CR generated by

Indexed as

AnimalsCell Line, TumorFluorodeoxyglucose F18HumansImmunotherapyLiverMicePhototherapyXenograft Model Antitumor AssaysFluorodeoxyglucose F1818F-FDGCerenkov radiationphotoimmunotherapyUV-A light

Identifiers

PMID28408528
PMCPMC5577626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.