Evidence map›Paper›PMID 28408482›Full record

ReviewBiochemical Society transactions2017

Small regulatory bacterial RNAs regulating the envelope stress response.

Gracjana Klein, Satish Raina

Open access · hybridAbstract readReview
In one paragraph

Review in Biochemical Society transactions, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 40 citations in OpenAlex.

  1. Essential Role of LapD in the Absence of Cardiolipins.International journal of molecular sciences · 2026
    Article
  2. Review
  3. Copper-induced stress mechanisms inApplied and environmental microbiology · 2025
    Article
  4. Article
  5. NsrR Represses σInternational journal of molecular sciences · 2025
    Article
  6. Article
  7. Article
  8. Quorum sensingHeliyon · 2023
    Article
  9. Article
  10. Review
  11. Review
  12. TheFrontiers in molecular biosciences · 2022
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Article
  18. Impacts of Small RNAs and Their Chaperones on Bacterial Pathogenicity.Frontiers in cellular and infection microbiology · 2021
    Review
  19. The Regulatory RNAFrontiers in microbiology · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Gracjana KleinUnit of Bacterial Genetics, Gdansk University of Technology, Narutowicza 11/12, 80-233 Gdansk, Poland.
Satish RainaUnit of Bacterial Genetics, Gdansk University of Technology, Narutowicza 11/12, 80-233 Gdansk, Poland satish.raina@pg.gda.pl.
Gdańsk University of Technology · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Most bacteria encode a large repertoire of RNA-based regulatory mechanisms. Recent discoveries have revealed that the expression of many genes is controlled by a plethora of base-pairing noncoding small regulatory RNAs (sRNAs), regulatory RNA-binding proteins and RNA-degrading enzymes. Some of these RNA-based regulated processes respond to stress conditions and are involved in the maintenance of cellular homeostasis. They achieve it by either direct posttranscriptional repression of several mRNAs, including blocking access to ribosome and/or directing them to RNA degradation when the synthesis of their cognate proteins is unwanted, or by enhanced translation of some key stress-regulated transcriptional factors. Noncoding RNAs that regulate the gene expression by binding to regulatory proteins/transcriptional factors often act negatively by sequestration, preventing target recognition. Expression of many sRNAs is positively regulated by stress-responsive sigma factors like RpoE and RpoS, and two-component systems like PhoP/Q, Cpx and Rcs. Some of these regulatory RNAs act via a feedback mechanism on their own regulators, which is best reflected by recent discoveries, concerning the regulation of cell membrane composition by sRNAs in

Indexed as

Bacterial ProteinsEscherichia coliGene Expression Regulation, BacterialRNA, BacterialRNA, Small UntranslatedRNA StabilitySalmonellaSigma FactorStress, PhysiologicalBacterial ProteinsRNA, BacterialRNA, Small UntranslatedSigma Factorenvelope stressnoncoding RNARfaHRpoE sigma factorstress responsetwo-component system

Identifiers

PMID28408482
PMCPMC5736990
OpenAlexW2607154987

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.