Observational studyArteriosclerosis, thrombosis, and vascular biology2017
Association of Air Pollution Exposures With High-Density Lipoprotein Cholesterol and Particle Number: The Multi-Ethnic Study of Atherosclerosis.
Open access · bronzeAbstract readMulticenter StudyObservational Study
In one paragraph
Observational study in Arteriosclerosis, thrombosis, and vascular biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.
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45citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
What it found
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The trial behind it
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Who cites it
45 citing papers in PubMed, 104 citations in OpenAlex.
- Association between PMBMC public health · 2026Article
- Diesel exhaust induces gut microbiome dysbiosis and reduced fecal acetate: Role of acetate supplementation.Ecotoxicology and environmental safety · 2025Article
- Air pollution and cognitive performance in late life: the role of lipid profile - results from the Multi-Ethnic Study of Atherosclerosis (MESA).Environment international · 2025Article
- Space for improvement: ZIP codes should not determine cardiovascular longevity, a scoping review.Trends in cardiovascular medicine · 2025Article
- Long-Term Exposure to Ambient Air Pollution and Metabolic Syndrome and Its Components.Journal of obesity & metabolic syndrome · 2025Review
- Association between air pollution and cardiovascular disease risk in middle-aged and elderly individuals with diabetes: inflammatory lipid ratio accelerate this progression.Diabetology & metabolic syndrome · 2025Article
- Air Pollution in Cardio-Oncology and Unraveling the Environmental Nexus:JACC. CardioOncology · 2024Review
- Longitudinal associations between ambient PMEnvironmental epidemiology (Philadelphia, Pa.) · 2024Article
- Article
- The Impact of Climate Change and Extreme Weather Conditions on Cardiovascular Health and Acute Cardiovascular Diseases.Journal of clinical medicine · 2024Review
- Structural and social determinants of health: The multi-ethnic study of atherosclerosis.PloS one · 2024Article
- Traffic Density Exposure, Oxidative Stress Biomarkers and Plasma Metabolomics in a Population-Based Sample: The Hortega Study.Antioxidants (Basel, Switzerland) · 2023Article
- Integrating 4-D light-sheet fluorescence microscopy and genetic zebrafish system to investigate ambient pollutants-mediated toxicity.The Science of the total environment · 2023Review
- Environmental exposures and blood pressure in adolescents and adults in the T1D exchange clinic registry.Journal of diabetes and its complications · 2023Article
- Identifying the Relationship between PMToxics · 2023Article
- Assessing the timing and the duration of exposure to air pollution on cardiometabolic biomarkers in patients suspected of coronary artery disease.Environmental research · 2023Article
- Effects of short-term PMScientific reports · 2023Article
- Modern Concepts of the Role of Fine Particles (PM 2.5) in the Genesis of Atherosclerosis and Myocardial Damage: Clinical and Epidemiological Data, the Main Pathophysiological Mechanisms.Current cardiology reviews · 2023Review
- Causality of particulate matter on cardiovascular diseases and cardiovascular biomarkers.Frontiers in public health · 2023Article
- Air Pollution: Another Threat to HDL Function.International journal of molecular sciences · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 3 institutions in 1 country.
Griffith BellFrom the Department of Epidemiology, University of Washington School of Public Health, Seattle (G.B., J.D.K.); Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.M.); Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (P.G.); Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis (M.T.); and Department of Medicine, University of Washington School of Medicine, Seattle (E.G., J.D.K.). grbell@uw.edu.
Samia MoraFrom the Department of Epidemiology, University of Washington School of Public Health, Seattle (G.B., J.D.K.); Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.M.); Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (P.G.); Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis (M.T.); and Department of Medicine, University of Washington School of Medicine, Seattle (E.G., J.D.K.).
Philip GreenlandFrom the Department of Epidemiology, University of Washington School of Public Health, Seattle (G.B., J.D.K.); Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.M.); Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (P.G.); Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis (M.T.); and Department of Medicine, University of Washington School of Medicine, Seattle (E.G., J.D.K.).
Michael TsaiFrom the Department of Epidemiology, University of Washington School of Public Health, Seattle (G.B., J.D.K.); Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.M.); Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (P.G.); Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis (M.T.); and Department of Medicine, University of Washington School of Medicine, Seattle (E.G., J.D.K.).
Ed GillFrom the Department of Epidemiology, University of Washington School of Public Health, Seattle (G.B., J.D.K.); Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.M.); Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (P.G.); Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis (M.T.); and Department of Medicine, University of Washington School of Medicine, Seattle (E.G., J.D.K.).
Joel D KaufmanFrom the Department of Epidemiology, University of Washington School of Public Health, Seattle (G.B., J.D.K.); Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA (S.M.); Department of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL (P.G.); Department of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis (M.T.); and Department of Medicine, University of Washington School of Medicine, Seattle (E.G., J.D.K.).
Northwestern University · USUniversity of Minnesota · USUniversity of Washington · US
Funding
Institute for Clinical and Translational ResearchUL1TR001079 · NCATS · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2013 to 2017
$60.1MXENOBIOTIC BIOTRANSFORMATION AND DISPOSITIONP30ES007033 · NIEHS · UNIVERSITY OF WASHINGTON · PI Sheela Sathyanarayana · 1995 to 2026
$42.5MClinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2MPulmonary microvascular perfusion in the Multi-Ethnic Study of AtherosclerosisR01HL077612 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI R Graham BARR · 2004 to 2026
$18.8MProject 5: ROS, Glutathione and Vascular Response to Diesel ExhaustP50ES015915 · NIEHS · UNIVERSITY OF WASHINGTON · PI KAVANAGH, TERRANCE J · 2008 to 2012
$11.8MFish Oil Intake, Biomarkers and Change in Lung FunctionR01HL075476 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BARR, R GRAHAM · 2004 to 2008
$2.8MEnvironmental Factors in Cardiovascular DiseaseK24ES013195 · NIEHS · UNIVERSITY OF WASHINGTON · PI KAUFMAN, JOEL DANIEL · 2005 to 2014
$1.5MAdjunctive Use of Apyrase to Fibrinolytic TherapyR44HL095169 · NHLBI · APT THERAPEUTICS, INC. · PI CHEN, RIDONG · 2012 to 2013
$1.3MMultidisciplinary Clinical and Translational Science (MCTS) Program (KL2)KL2TR000107 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI LLOYD-JONES, DONALD M · 2012 to 2013
$1.1MSUBCLINICAL CARDIOVASCULAR DISEASE STUDYN01HC095166 · HC · UNIVERSITY OF VERMONT &ST AGRIC COLLEGE · PI TRACY, RUSSELL P · 1999 to 2001
$758kSUBCLINICAL CARDIOVASCULAR DISEASE STUDY-FIELD CENTERN01HC095162 · HC · JOHNS HOPKINS UNIVERSITY · PI SZKLO, MOYSES A · 1999 to 2000
$694kSUBCLINICAL CARDIOVASCULAR DISEASE STUDY--FIELD CENTERN01HC095161 · HC · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SHEA, STEVEN · 1999 to 2001
$642kNCATS NIH HHS KL2 TR000107NCATS NIH HHS UL1 TR000040NCATS NIH HHS UL1 TR001079NHLBI NIH HHS N01 HC095159NHLBI NIH HHS N01 HC095160NHLBI NIH HHS N01 HC095161NHLBI NIH HHS N01 HC095162NHLBI NIH HHS N01 HC095163NHLBI NIH HHS N01 HC095164NHLBI NIH HHS N01 HC095165NHLBI NIH HHS N01 HC095166NHLBI NIH HHS N01 HC095167NHLBI NIH HHS N01 HC095168NHLBI NIH HHS N01 HC095169NHLBI NIH HHS R01 HL075476NHLBI NIH HHS R01 HL077612NIEHS NIH HHS F31 ES025096NIEHS NIH HHS K24 ES013195NIEHS NIH HHS P30 ES007033NIEHS NIH HHS P50 ES015915
Abstract
objectiveThe relationship between air pollution and cardiovascular disease may be explained by changes in high-density lipoprotein (HDL). APPROACH AND
resultsWe examined the cross-sectional relationship between air pollution and both HDL cholesterol and HDL particle number in the MESA Air study (Multi-Ethnic Study of Atherosclerosis Air Pollution). Study participants were 6654 white, black, Hispanic, and Chinese men and women aged 45 to 84 years. We estimated individual residential ambient fine particulate pollution exposure (PM
conclusionsThese data are consistent with the hypothesis that exposure to air pollution is adversely associated with measures of HDL.
Indexed as
AgedAged, 80 and overAir PollutantsAsianAtherosclerosisBiomarkersBlack or African AmericanCholesterol, HDLCross-Sectional StudiesEnvironmental ExposureFemaleHispanic or LatinoHumansLinear ModelsMaleMiddle AgedAir PollutantsBiomarkersCholesterol, HDLair pollutioncholesterolcohort studyhigh-density lipoproteinhigh-density lipoprotein cholesterol
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.