Evidence map›Paper›PMID 28408072›Full record

ArticleWomen's health issues : official publication of the Jacobs Institute of Women's Health

Nonmedical Use of Prescription Opioids among Pregnant U.S. Women.

Katy B Kozhimannil, Amy J Graves, Robert Levy, Stephen W Patrick

Abstract read
In one paragraph

Article in Women's health issues : official publication of the Jacobs Institute of Women's Health. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Predictors of Opioid Misuse and Abuse Among Pregnant Women in the US.Pain management nursing : official journal of the American Society of Pain Management Nurses · 2026
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  16. Perinatal Behavioral Health, the COVID-19 Pandemic, and a Social Determinants of Health Framework.Journal of obstetric, gynecologic, and neonatal nursing : JOGNN · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Katy B KozhimannilDivision of Health Policy and Management, University of Minnesota School of Public Health, Minneapolis, Minnesota. Electronic address: kbk@umn.edu.
Amy J GravesDivision of Health Policy and Management, University of Minnesota School of Public Health, Minneapolis, Minnesota.
Robert LevyDepartment of Family Medicine and Community Health, University of Minnesota Medical School, Minneapolis, Minnesota.
Stephen W PatrickDepartment of Pediatrics, Vanderbilt University School of Medicine, Nashville, Tennessee; Department of Health Policy, Vanderbilt Center for Health Services Research, Vanderbilt University School of Medicine, Nashville, Tennessee.

Funding

Neonatal Abstinence Syndrome: Risk of Drug Withdrawal in Opioid-Exposed InfantsK23DA038720 · NIDA · VANDERBILT UNIVERSITY MEDICAL CENTER · PI PATRICK, STEPHEN W · 2015 to 2019
$844k
NIDA NIH HHS K23 DA038720
6 · The paper itself

Abstract

objectivesNonmedical use of opioids during pregnancy is associated with adverse outcomes for women and infants, making it a prominent target for prevention and identification. Using a nationally representative sample, we determined characteristics of U.S. pregnant women who reported prescription opioid misuse in the past year or during the past month.

methodsWe used data from the National Survey on Drug Use and Health (2005-2014) in a retrospective analysis. The sample included 8,721 (weighted n = 23,855,041) noninstitutionalized women, ages 12 to 44, who reported being pregnant when surveyed. Outcomes were nonmedical use of prescription opioid medications during the past 12 months and during the past 30 days. Multivariable logistic regression models were created to determine correlates of nonmedical opioid use after accounting for potential confounding variables.

resultsAmong pregnant women in the United States, 5.1% reported nonmedical opioid use in the past year. In adjusted models, depression or anxiety in the past year was strongly associated with past year nonmedical use (adjusted odd ratio [AOR], 2.15; 95% CI, 1.52-3.04), as were past year use of alcohol (AOR, 1.56; 95% CI, 1.11-2.17), tobacco (AOR, 1.72; 95% CI, 1.17-2.53), and marijuana (AOR, 3.44; 95% CI, 2.47-4.81). Additionally, 0.9% of U.S. pregnant women reported nonmedical opioid use in the past month. Past year depression or anxiety and past month use of alcohol, tobacco, and marijuana each independently predicted past month nonmedical use.

conclusionsCharacteristics associated with nonmedical opioid use by pregnant women reveal populations with mental illness and co-occurring substance use. Policy and prevention efforts to improve screening and treatment could focus on the at-risk populations identified in this study.

Indexed as

Analgesics, OpioidCentral Nervous System StimulantsPrescription Drug MisusePrescription DrugsAdolescentAdultChildFemaleHealth SurveysHumansLogistic ModelsOpioid-Related DisordersPregnancyRetrospective StudiesUnited StatesYoung AdultAnalgesics, OpioidCentral Nervous System StimulantsPrescription Drugs

Identifiers

PMID28408072
PMCPMC5435501

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.