Evidence map›Paper›PMID 28407842›Full record

ArticleDeutsches Arzteblatt international2017

The Prevalence of Glaucoma in Young People.

Susanne Marx-Gross, Dagmar Laubert-Reh, Astrid Schneider, René Höhn, Alireza Mirshahi, Thomas Münzel, Philipp S Wild, Manfred E Beutel, Maria Blettner, Norbert Pfeiffer

Abstract read
In one paragraph

Article in Deutsches Arzteblatt international, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Observational
  10. The Diagnosis and Treatment of Glaucoma.Deutsches Arzteblatt international · 2020
    Review
  11. OCT and IOP findings in a healthy worker cohort: results from a teleophthalmic study in occupational medicine.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2019
    Article
  12. [Ophthalmology 2019-where do we stand? : An analysis of the treatment situation in Germany].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2019
    Review
  13. [Glaucoma in inpatient care in Germany in 2015].Der Ophthalmologe : Zeitschrift der Deutschen Ophthalmologischen Gesellschaft · 2019
    Article
  14. Article
  15. Increase in Glaucoma Patients.Deutsches Arzteblatt international · 2017
    Article
  16. Article
  17. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Susanne Marx-GrossDepartment of Ophthalmology, University Medical Center of the Johannes Gutenberg University Mainz; Department of Preventive Cardiology and Preventive Medicine, Cardiology I,University Medical Center of the Johannes Gutenberg University Mainz; Department of Opththalmology, Inselspital, University of Bern, Switzerland; Dardenne Eye Hospital; Cardiology I,University Medical Center of the Johannes Gutenberg University Mainz; Center for Thrombosis and Hemostasis, University Medical Center of the Johannes Gutenberg University Mainz; German Center for Cardiovascular Disease (DZHK), Mainz; Department of Psychosomatic Medicine and Psychotherapy, University Medical Center, Johannes Gutenberg University Mainz; Institute of Medical Biostatistics, Epidemiology and Informatics (IMBEI), University Medical Center of the Johannes Gutenberg University Mainz; Artemiskliniken, Frankfurt.
Dagmar Laubert-Reh
Astrid Schneider
René Höhn
Alireza Mirshahi
Thomas Münzel
Philipp S Wild
Manfred E Beutel
Maria Blettner
Norbert Pfeiffer
Johannes Gutenberg University Mainz · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEarlier information on the prevalence of glaucoma among children in Germany was based solely on estimates. Reported values for congenital glaucoma range from 1 in 10 000 to 1 in 68 000 depending on ethnic origin. The estimate for juvenile glaucoma is 1 in 44 000.

methodsThe Gutenberg Health Study is a populationbased, prospective, monocentric cohort study with 15 010 participants aged 35 to 74. To determine the history-based prevalence of childhood glaucoma, participants were asked about the diagnosis of glaucoma, any operations for glaucoma that were performed, regular use of drugs for glaucoma, and the age of onset of glaucoma. The affected individuals were classified in four groups based on the age of onset: congenital (<2 years), juvenile (2 to <18 years), late juvenile (18 to <40 years), and early adult (40 to <45 years). In the identified glaucoma patients, the visual acuity, intraocular pressure, corneal thickness, visual fields, and optic discs were evaluated.

results352 persons were identified from their medical history as having glaucoma. The weighted prevalences in the four groups were 0% in the congenital group, 0.01% (95% confidence interval [0, 0.03]) in the juvenile group, 0.16 % ([0.09; 0.23]) in the late juvenile group, and 0.17% ([0.15; 0.19]) in the early adult group. For participants over age 45, the weighted prevalence of glaucoma was 1.98% [1.7; 2.2].

conclusionIn our cohort, the history-based prevalence of juvenile glaucoma was 0.01% (2 patients). The prevalence was an order of magnitude higher (0.16%) between the ages of 18 and 40, and two orders of magnitude higher at later ages (1.98%). The burden of disease seems to be markedly higher than previously assumed.

Indexed as

AdolescentAdultAgedChildChild, PreschoolCross-Sectional StudiesGermanyGlaucomaGlaucoma, Open-AngleHumansInfantIntraocular PressureMiddle AgedPrevalenceProspective StudiesYoung Adult

Identifiers

PMID28407842
PMCPMC5397891
OpenAlexW2801344602

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.