Evidence map›Paper›PMID 28407641›Full record

ArticleSexually transmitted diseases2017

Adverse Birth Outcomes and Maternal Neisseria gonorrhoeae Infection: A Population-Based Cohort Study in Washington State.

Christine L Heumann, Laura A S Quilter, McKenna C Eastment, Renee Heffron, Stephen E Hawes

Abstract read
In one paragraph

Article in Sexually transmitted diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 1 synthesis or guideline pooled it, 85 citations in OpenAlex.

  1. Adverse pregnancy and neonatal outcomes associated withSexually transmitted infections · 2021
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
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  8. Article
  9. Article
  10. Experimental Urethral Infection with Neisseria gonorrhoeae.Current topics in microbiology and immunology · 2024
    Review
  11. Journal of clinical medicine · 2023
    Review
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  19. Observational
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Christine L HeumannFrom the *Division of Infectious Diseases, Department of Medicine, Wayne State University, Detroit, MI; †Division of Allergy and Infectious Diseases, Department of Medicine, ‡Department of Global Health, and §Department of Epidemiology, University of Washington, Seattle, WA.
Laura A S Quilter
McKenna C Eastment
Renee Heffron
Stephen E Hawes
University of Washington · USWayne State University · US

Funding

VENEREAL DISEASET32AI007140 · NIAID · UNIVERSITY OF WASHINGTON · PI Julia Cook Dombrowski · 1985 to 2026
$19.4M
HOST DEFENSE TRAINING IN ALLERGY AND INFECTIOUS DISEASEST32AI007044 · NIAID · UNIVERSITY OF WASHINGTON · PI DAVID Neal FREDRICKS · 1985 to 2026
$14.6M
SEATTLE STD CLINICAL PREVENTION TRAINING CENTERU62PS004584 · PS · UNIVERSITY OF WASHINGTON · PI JOHNSTON, CHRISTINE MICHELLE · 2014 to 2015
$1.3M
NCHHSTP CDC HHS U62 PS004584NIAID NIH HHS T32 AI007044NIAID NIH HHS T32 AI007140
6 · The paper itself

Abstract

backgroundNeisseria gonorrhoeae (gonorrhea) remains an important cause of reproductive and obstetric complications. There has been limited population-based research to evaluate the association between maternal gonorrhea and adverse birth outcomes.

methodsA population-based retrospective cohort study was conducted of women with singleton pregnancies in Washington State from 2003 to 2014 using linked birth certificate and birth hospitalization discharge data. The exposed cohort consisted of women with gonorrhea diagnosed during pregnancy. The unexposed group, defined as pregnant women without gonorrhea, was selected by frequency-matching by birth year in a 4:1 ratio. Logistic regression was used to determine crude and adjusted odds ratios (OR) for the association of maternal gonorrhea and adverse birth outcomes.

resultsWomen with gonorrhea during pregnancy (N = 819) were more likely to be younger, black, single, less educated, multiparous, and smokers compared with women without gonorrhea (N = 3276). Maternal gonorrhea was significantly associated with a 40% increased odds (adjusted OR, 1.4; 95% confidence interval [CI], 1.0-1.8) of low birth weight infants compared with women without gonorrhea when adjusted for marital and smoking status. Maternal gonorrhea was associated with a 60% increased odds (OR, 1.6; 95% CI, 1.3-2.0) of small for gestational age infants compared with women without gonorrhea.

conclusionsThis analysis showed that pregnant women with gonorrhea were more likely to have low birth weight infants, consistent with prior literature, and provided new evidence that maternal gonorrhea is associated with small for gestational age infants. These findings support increased public health efforts to prevent, identify, and treat gonorrhea infection during pregnancy.

Indexed as

AdultChorioamnionitisCohort StudiesFemaleGonorrheaHumansInfantInfant, Low Birth WeightInfant, NewbornIntensive Care Units, NeonatalMaternal AgeMedical RecordsNeisseria gonorrhoeaeOdds RatioPregnancyPregnancy Complications, Infectious

Identifiers

PMID28407641
PMCPMC5407319
OpenAlexW2593341637

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.