Evidence map›Paper›PMID 28407501›Full record

ArticleEcotoxicology and environmental safety2017

Transcriptional changes in innate immunity genes in head kidneys from Aeromonas salmonicida-challenged rainbow trout fed a mixture of polycyclic aromatic hydrocarbons.

Lawrence R Curtis, Claudia F Bravo, Christopher J Bayne, Fred Tilton, Mary R Arkoosh, Elisabetta Lambertini, Frank J Loge, Tracy K Collier, James P Meador, Susan C Tilton

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Ecotoxicology and environmental safety, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Lawrence R CurtisDepartment of Environmental and Molecular Toxicology, Oregon State University, ALS 1007, Corvallis, OR 97331, USA.
Claudia F BravoDepartment of Environmental and Molecular Toxicology, Oregon State University, ALS 1007, Corvallis, OR 97331, USA.
Christopher J BayneDepartment of Integrative and Comparative Biology, Oregon State University, Cordley 3029, Corvallis, OR 97331, USA.
Fred TiltonDepartment of Environmental and Molecular Toxicology, Oregon State University, ALS 1007, Corvallis, OR 97331, USA.
Mary R ArkooshEnvironmental & Fisheries Sciences Division, Northwest Fisheries Science Center, National Marine Fisheries Service, National Oceanic and Atmospheric Administration, 2030 South Marine Science Drive, Newport, OR 97365, USA.
Elisabetta LambertiniDepartment of Civil and Environmental Engineering, University of California Davis, 1 Shields Ave, Davis, CA 9561, USA.
Frank J LogeDepartment of Civil and Environmental Engineering, University of California Davis, 1 Shields Ave, Davis, CA 9561, USA.
Tracy K CollierEnvironmental & Fisheries Sciences Division, Northwest Fisheries Science Center, National Marine Fisheries Service, National Oceanic and Atmospheric Administration, 2727 Montlake Boulevard East, Seattle, WA 98112, USA.
James P MeadorEnvironmental & Fisheries Sciences Division, Northwest Fisheries Science Center, National Marine Fisheries Service, National Oceanic and Atmospheric Administration, 2727 Montlake Boulevard East, Seattle, WA 98112, USA.
Susan C TiltonDepartment of Environmental and Molecular Toxicology, Oregon State University, ALS 1007, Corvallis, OR 97331, USA. Electronic address: susan.tilton@oregonstate.edu.
Oregon State University · USNOAA National Marine Fisheries Service Northwest Fisheries Science Center · USUniversity of California, Davis · USNational Oceanic and Atmospheric Administration · US

Funding

Research Experience and Training Coordination CoreP42ES016465 · NIEHS · OREGON STATE UNIVERSITY · PI Susan C Tilton · 2009 to 2026
$52.5M
THE ROLE OF ENDOCANNABINOIDS AND THEIR RECEPTORS IN COLORECTAL CANCERP01CA077839 · NCI · VANDERBILT UNIVERSITY · PI DUBOIS, RAYMOND N. · 1999 to 2016
$17.8M
THE PHARMACOLOGY OF INHIBITORS OF HEME PROTEIN-CATALYZED LIPID PEROXIDATIONP50GM015431 · NIGMS · VANDERBILT UNIVERSITY · PI CAPRIOLI, RICHARD M · 1985 to 2010
$15.0M
Protein Adducts and Proteome Profiles in Oxidative StressP01ES013125 · NIEHS · VANDERBILT UNIVERSITY · PI PORTER, NED ALLEN · 2005 to 2012
$12.6M
Therapeutic Modulation of Endothelial Cell TetrahydrobiopterinP01GM015431 · NIGMS · VANDERBILT UNIVERSITY · PI MARNETT, LAWRENCE J. · 2011 to 2015
$9.5M
AHR Signaling in Mammalian and Non-Mammalian ModelsR01ES006272 · NIEHS · WOODS HOLE OCEANOGRAPHIC INSTITUTION · PI HAHN, MARK E · 1999 to 2014
$4.1M
BIOCHEMISTRY AND PHARMACOLOGY OF D2/E2-ISOPROSTANESR01DK048831 · NIDDK · VANDERBILT UNIVERSITY · PI YIN, HUIYONG · 1995 to 2008
$2.2M
NCI NIH HHS P01 CA077839NIDDK NIH HHS R01 DK048831NIEHS NIH HHS P01 ES013125NIEHS NIH HHS P42 ES016465NIEHS NIH HHS R01 ES006272NIGMS NIH HHS P01 GM015431NIGMS NIH HHS P50 GM015431
6 · The paper itself

Abstract

We previously observed that exposure to a complex mixture of high molecular weight polycyclic aromatic hydrocarbons (PAHs) increased sensitivity of rainbow trout (Oncorhynchus mykiss) to subsequent challenge with Aeromonas salmonicida, the causative agent of furunculosis. In this study, we evaluate potential mechanisms associated with disease susceptibility from combined environmental factors of dietary PAH exposure and pathogen challenge. Rainbow trout were fed a mixture of ten high molecular weight PAHs at an environmentally relevant concentration (7.82μg PAH mixture/g fish/day) or control diet for 50 days. After 50 days of PAH exposure, fish were challenged with either Aeromonas salmonicida at a lethal concentration 30 (LC

Indexed as

Aeromonas salmonicidaAnimalsDown-RegulationHead KidneyImmunity, InnateMuramidaseOncorhynchus mykissPolycyclic Aromatic HydrocarbonsTranscription, GeneticMuramidasePolycyclic Aromatic HydrocarbonsDisease susceptibilityInnate immunityPolycyclic aromatic hydrocarbon mixtureTranscriptomics. Rainbow trout

Identifiers

PMID28407501
PMCPMC7039304
OpenAlexW2607088364

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.