Evidence map›Paper›PMID 28407345›Full record

ArticleJournal of applied clinical medical physics2017

Dosimetric impacts of endorectal balloon in CyberKnife stereotactic body radiation therapy (SBRT) for early-stage prostate cancer.

Hong F Xiang, Hsiao-Ming Lu, Jason A Efstathiou, Anthony L Zietman, Ricardo De Armas, Kathryn Harris, B Nicolas Bloch, Muhammad Mustafa Qureshi, Sean Keohan, Ariel E Hirsch

Abstract read
In one paragraph

Article in Journal of applied clinical medical physics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. The role and importance of SBRT in prostate cancer.International braz j urol : official journal of the Brazilian Society of Urology
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hong F XiangDepartment of Radiation Oncology, Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts, USA.
Hsiao-Ming LuDepartment of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Jason A EfstathiouDepartment of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Anthony L ZietmanDepartment of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Ricardo De ArmasMassachusetts Institute of Technology, Cambridge, Massachusetts, USA.
Kathryn HarrisMassachusetts Institute of Technology, Cambridge, Massachusetts, USA.
B Nicolas BlochDepartment of Radiation Oncology, Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts, USA.
Muhammad Mustafa QureshiDepartment of Radiation Oncology, Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts, USA.
Sean KeohanDepartment of Radiation Oncology, Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts, USA.
Ariel E HirschDepartment of Radiation Oncology, Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIn SBRT for prostate cancer, higher fractional dose to the rectum is a major toxicity concern due to using smaller PTV margin and hypofractionation. We investigate the dosimetric impact on rectum using endorectal balloon (ERB) in prostate SBRT. MATERIALS AND

methodsTwenty prostate cancer patients were included in a retrospective study, ten with ERB and 10 without ERB. Optimized SBRT plans were generated on CyberKnife MultiPlan for 5 × 7.25 Gy to PTV under RTOG-0938 protocol for early-stage prostate cancer. For the rectum and the anterior half rectum, mean dose and percentage of volumes receiving 50%, 80%, 90%, and 100% prescription dose were compared.

resultsUsing ERB, mean dose to the rectum was 62 cGy (P = 0.001) lower per fraction, and 50 cGy (P = 0.024) lower per fraction for the anterior half rectum. The average V

conclusionsSignificant reductions of dose to the rectum using ERB were observed. This may lead to improvement of the rectal toxicity profiles in prostate SBRT.

Indexed as

HumansMaleProstatic NeoplasmsRadiation DosageRadiation InjuriesRadiometryRadiosurgeryRectumRetrospective StudiesCyberKnifeendorectal balloonprostate cancerrectum toxicitySBRT

Identifiers

PMID28407345
PMCPMC5689864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.