ArticleMolecular biology and evolution2017
Non-Random Inversion Landscapes in Prokaryotic Genomes Are Shaped by Heterogeneous Selection Pressures.
Article in Molecular biology and evolution, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Evolutionary constraints on RNA polymerase gene positioning in the genome of fast-growing bacteria.Nucleic acids research · 2026Article
- Insertion sequence elements and unique symmetrical genomic regions mediate chromosomal inversions in Streptococcus pyogenes.Nucleic acids research · 2024Article
- Article
- Replication-associated inversions are the dominant form of bacterial chromosome structural variation.Life science alliance · 2023Article
- Replication-Dependent Organization Constrains Positioning of Long DNA Repeats in Bacterial Genomes.Genome biology and evolution · 2022Article
- Genomic structural plasticity of rodent-associated Bartonella in nature.Molecular ecology · 2022Article
- Positive Selection during Niche Adaptation Results in Large-Scale and Irreversible Rearrangement of Chromosomal Gene Order in Bacteria.Molecular biology and evolution · 2022Article
- Characterization of gross genome rearrangements in Deinococcus radiodurans recA mutants.Scientific reports · 2021Article
- Comparative in silico genome analysis of Clostridium perfringens unravels stable phylogroups with different genome characteristics and pathogenic potential.Scientific reports · 2021Article
- Article
- Genomic rearrangements uncovered by genome-wide co-evolution analysis of a major nosocomial pathogen,Microbial genomics · 2020Article
- Macromolecular crowding links ribosomal protein gene dosage to growth rate in Vibrio cholerae.BMC biology · 2020Article
- Micro-evolution of three Streptococcus species: selection, antigenic variation, and horizontal gene inflow.BMC evolutionary biology · 2019Article
- Comparative Genomics ofFrontiers in microbiology · 2019Article
- Genome rearrangements and selection in multi-chromosome bacteria Burkholderia spp.BMC genomics · 2018Article
- Evolution of Genome Architecture in Archaea: Spontaneous Generation of a New Chromosome in Haloferax volcanii.Molecular biology and evolution · 2018Article
- Chromosome architecture constrains horizontal gene transfer in bacteria.PLoS genetics · 2018Article
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2 authors.
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Abstract
Inversions are a major contributor to structural genome evolution in prokaryotes. Here, using a novel alignment-based method, we systematically compare 1,651 bacterial and 98 archaeal genomes to show that inversion landscapes are frequently biased toward (symmetric) inversions around the origin-terminus axis. However, symmetric inversion bias is not a universal feature of prokaryotic genome evolution but varies considerably across clades. At the extremes, inversion landscapes in Bacillus-Clostridium and Actinobacteria are dominated by symmetric inversions, while there is little or no systematic bias favoring symmetric rearrangements in archaea with a single origin of replication. Within clades, we find strong but clade-specific relationships between symmetric inversion bias and different features of adaptive genome architecture, including the distance of essential genes to the origin of replication and the preferential localization of genes on the leading strand. We suggest that heterogeneous selection pressures have converged to produce similar patterns of structural genome evolution across prokaryotes.
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