ArticlePLoS pathogens2017
Arabidopsis leucine-rich repeat receptor-like kinase NILR1 is required for induction of innate immunity to parasitic nematodes.
Article in PLoS pathogens, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.
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Who cites it
85 citing papers in PubMed, 190 citations in OpenAlex.
- Auxin-responsive SlXTH3 promotes Ralstonia solanacearum infection by modulating lateral root development and root immunity in tomato.Plant cell reports · 2026Article
- miR169f regulation by lncRNA LASSO fine-tunes JA-dependent root immunity in rice.The New phytologist · 2026Article
- Redox Regulation of Plant-Root-Knot Nematode Interactions: From ROS-Mediated Immunity to Sustainable Resistance.Antioxidants (Basel, Switzerland) · 2026Review
- Integrative approach to identify robust pattern recognition receptors in Eucalyptus grandis: novel candidates for disease resistance.Plant molecular biology · 2026Article
- The conserved nematode pheromone ascr#18 primes plant immunity.Communications biology · 2026Article
- Current Understanding of Cell-Surface Immune Receptors for MAMPs and Plant Parasites in the Solanaceae Family.Molecular plant pathology · 2026Review
- Toward sustainable control of phyto-nematodes: integrating lessons from crops to advance genetic modification in tomato.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Review
- A weighted gene co-expression network analysis characterises the common defence responses of Eucalyptus to diverse biotic challenges.Scientific reports · 2026Article
- Rethinking control strategies for plant-parasitic nematodes.Journal of nematology · 2026Article
- Deciphering the underlying genetics of galling resistance to the blueberry stem gall wasp in northern highbush blueberry.Horticulture research · 2025Article
- Article
- Pre-Crop Choice Shapes Nematode-Attached Bacterial Communities Associated With Reduced Pratylenchus penetrans Invasion of Barley Roots.Environmental microbiology · 2025Article
- A trehalase-derived MAMP triggers LecRK-V-mediated immune responses inScience advances · 2025Article
- Nematode Pheromones as Key Mediators of Behavior, Development, and Ecological Interactions.Biomolecules · 2025Review
- CaEMBO reports · 2025Article
- Combating Root-Knot Nematodes (Plants (Basel, Switzerland) · 2025Review
- Clade V MLO Genes Are Negative Modulators of Cucumber Defence Response to Meloidogyne incognita.Molecular plant pathology · 2025Article
- Mitochondrial Protein MjEF-Tu is Secreted into Host Plants by Nematodes Eliciting Immune Signaling and Resistance.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- The receptor MIK2 interacts with the kinase RKS1 to control quantitative disease resistance to Xanthomonas campestris.Plant physiology · 2024Article
- A novel LRR receptor-like kinase BRAK reciprocally phosphorylates PSKR1 to enhance growth and defense in tomato.The EMBO journal · 2024Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Plant-parasitic nematodes are destructive pests causing losses of billions of dollars annually. An effective plant defence against pathogens relies on the recognition of pathogen-associated molecular patterns (PAMPs) by surface-localised receptors leading to the activation of PAMP-triggered immunity (PTI). Extensive studies have been conducted to characterise the role of PTI in various models of plant-pathogen interactions. However, far less is known about the role of PTI in roots in general and in plant-nematode interactions in particular. Here we show that nematode-derived proteinaceous elicitor/s is/are capable of inducing PTI in Arabidopsis in a manner dependent on the common immune co-receptor BAK1. Consistent with the role played by BAK1, we identified a leucine-rich repeat receptor-like kinase, termed NILR1 that is specifically regulated upon infection by nematodes. We show that NILR1 is essential for PTI responses initiated by nematodes and nilr1 loss-of-function mutants are hypersusceptible to a broad category of nematodes. To our knowledge, NILR1 is the first example of an immune receptor that is involved in induction of basal immunity (PTI) in plants or in animals in response to nematodes. Manipulation of NILR1 will provide new options for nematode control in crop plants in future.
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