Evidence map›Paper›PMID 28406893›Full record

ReviewNature chemical biology2017

The chemical basis for electrical signaling.

William A Catterall, Goragot Wisedchaisri, Ning Zheng

Abstract readReview
In one paragraph

Review in Nature chemical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

122 citing papers in PubMed.

  1. Review
  2. Voltage-sensing domains: structural and functional diversity.European biophysics journal : EBJ · 2026
    Review
  3. Biomolecules · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Structure of the human KNature structural & molecular biology · 2025
    Article
  16. Review
  17. Article
  18. Review
  19. Voltage sensors.Molecular pharmacology · 2025
    Review
  20. Review

62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

William A CatterallDepartment of Pharmacology, University of Washington, Seattle, Washington, USA.
Goragot WisedchaisriDepartment of Pharmacology, University of Washington, Seattle, Washington, USA.
Ning ZhengDepartment of Pharmacology, University of Washington, Seattle, Washington, USA.

Funding

Structural Basis for Antiarrhythmic Drug ActionR01HL112808 · NHLBI · UNIVERSITY OF WASHINGTON · PI ZHENG, NING · 2012 to 2025
$7.8M
VOLTAGE-SENSITIVE SODIUM CHANNELS IN BRAINR01NS015751 · NINDS · UNIVERSITY OF WASHINGTON · PI CATTERALL, WILLIAM A · 1985 to 2018
$6.0M
Structural Basis for Calcium Selectivity and Drug Block of Cav ChannelsR01HL117896 · NHLBI · UNIVERSITY OF WASHINGTON · PI CATTERALL, WILLIAM A, ZHENG, NING · 2014 to 2017
$1.5M
Howard Hughes Medical InstituteNHLBI NIH HHS R01 HL112808NHLBI NIH HHS R01 HL117896NINDS NIH HHS R01 NS015751
6 · The paper itself

Abstract

Electrical signals generated by minute currents of ions moving across cell membranes are central to all rapid processes in biology. Initiation and propagation of electrical signals requires voltage-gated sodium (Na

Indexed as

Electric ConductivityIon Channel GatingCalciumHumansIon ChannelsModels, MolecularPotassiumSodiumCalciumIon ChannelsPotassiumSodium

Identifiers

PMID28406893
PMCPMC5464002

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.