Evidence map›Paper›PMID 28406748›Full record

ArticleRadiation research2017

Radiation-Induced Dermatitis is Mediated by IL17-Expressing γδ T Cells.

Wupeng Liao, Tom K Hei, Simon K Cheng

Open access · bronzeAbstract read
In one paragraph

Article in Radiation research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Wupeng Liaoa   Department of Radiation Oncology.
Tom K Heib   Center for Radiological Research, College of Physicians and Surgeons, Columbia University, New York, New York 10032; and.
Simon K Chenga   Department of Radiation Oncology.
Columbia University · US

Funding

THE FUNCTIONAL GENOMICS OF BYSTANDER RESPONSESP01CA049062 · NCI · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI HEI, TOM K. · 1990 to 2014
$21.9M
Cytoplasmic Damage and GenotoxicityR01ES012888 · NIEHS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI HEI, TOM K. · 2004 to 2016
$3.9M
NCI NIH HHS P01 CA049062NIEHS NIH HHS R01 ES012888
6 · The paper itself

Abstract

Radiation dermatitis is a serious cutaneous injury caused by radiation therapy or upon accidental nuclear exposure. However, the pathogenic immune mechanisms underlying this injury are still poorly understood. We seek to discover how the dysregulated immune response after irradiation orchestrates skin inflammation. The skin on the left flank of C57BL/6J wild-type and C57BL/6J Tcrd

Indexed as

AnimalsHumansInflammationInterleukin-17KeratinocytesMiceMice, Inbred C57BLMice, KnockoutRadiation Injuries, ExperimentalRadiodermatitisReceptors, Antigen, T-Cell, gamma-deltaT-LymphocytesInterleukin-17Receptors, Antigen, T-Cell, gamma-delta

Identifiers

PMID28406748
PMCPMC5524538
OpenAlexW2586077816

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.