Evidence map›Paper›PMID 28406429›Full record

ArticleNanomaterials (Basel, Switzerland)2017

Release of Doxorubicin by a Folate-Grafted, Chitosan-Coated Magnetic Nanoparticle.

Chung-Lin Yang, Jyh-Ping Chen, Kuo-Chen Wei, Ju-Yu Chen, Chia-Wen Huang, Zi-Xian Liao

Open access · goldAbstract read
In one paragraph

Article in Nanomaterials (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 60 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Chung-Lin YangDepartment of Neurosurgery, Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan. a0955498306@gmail.com.
Jyh-Ping ChenDepartment of Chemical and Materials Engineering, Chang Gung University, Taoyuan 33305, Taiwan. jpchen@mail.cgu.edu.tw.
Kuo-Chen WeiDepartment of Neurosurgery, Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan. kuochenwei@adm.cgmh.org.tw.
Ju-Yu ChenDepartment of Neurosurgery, Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan. santuryqq@gmail.com.
Chia-Wen HuangDepartment of Neurosurgery, Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan. chiawen0712@gmail.com.
Zi-Xian LiaoInstitute of Medical Science and Technology, National Sun Yat-sen University, Kaohsiung 80424, Taiwan. zxliao@mail.nsysu.edu.tw.
Chang Gung Memorial Hospital · TWChang Gung University · TWNational Sun Yat-sen University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In clinical tumor therapy, chemotherapeutic routes have caused severe side effects; current delivery methods are unsatisfactory. Successful design of a remotely folate (FA)-grafted chitosan (CS)-coated magnetic nanoparticle (MNP) with low toxicity, has been achieved. A chemotherapeutic drug such as doxorubicin (DOX), is loaded in the MNP-based matrix (FA-grafted CS-DOX-

Indexed as

antitumor effectchitosandoxorubicinmagnetic nanoparticlesremote delivery

Identifiers

PMID28406429
PMCPMC5408177
OpenAlexW2607447897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.