Evidence map›Paper›PMID 28406245›Full record

ArticleScientific reports2017

Nanomechanics of the endothelial glycocalyx contribute to Na

Florian Schierke, Margot J Wyrwoll, Martin Wisdorf, Leon Niedzielski, Martina Maase, Tobias Ruck, Sven G Meuth, Kristina Kusche-Vihrog

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 53 citations in OpenAlex.

  1. Trial
  2. Salt and chronic kidney disease.Nature reviews. Nephrology · 2026
    Review
  3. Review
  4. Article
  5. New Frontiers in modeling the lipedema microenvironmentFrontiers in cell and developmental biology · 2026
    Review
  6. SECS, drugs, and Rac1&Rho: regulation of EnNaC in vascular endothelial cells.Pflugers Archiv : European journal of physiology · 2025
    Article
  7. The Interplay Between Immunity, Inflammation and Endothelial Dysfunction.International journal of molecular sciences · 2025
    Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Microvascular Thrombosis as a Critical Factor in Severe COVID-19.International journal of molecular sciences · 2023
    Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Florian SchierkeInstitute of Physiology II, University of Münster, 48149 Münster, Germany.
Margot J WyrwollInstitute of Physiology II, University of Münster, 48149 Münster, Germany.
Martin WisdorfInstitute of Physiology II, University of Münster, 48149 Münster, Germany.
Leon NiedzielskiInstitute of Physiology II, University of Münster, 48149 Münster, Germany.
Martina MaaseInstitute of Physiology II, University of Münster, 48149 Münster, Germany.
Tobias RuckDepartment of Neurology, University of Münster, 48149 Münster, Germany.
Sven G MeuthDepartment of Neurology, University of Münster, 48149 Münster, Germany.
Kristina Kusche-VihrogInstitute of Physiology II, University of Münster, 48149 Münster, Germany.
University of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High dietary salt (NaCl) is a known risk factor for cardiovascular pathologies and inflammation. High plasma Na

Indexed as

AnimalsBiomechanical PhenomenaCell AdhesionCells, CulturedEndothelial CellsGlycocalyxHumansInterleukin-1betaMaleMiceMonocytesNitric OxideSodium Chloride, DietaryTumor Necrosis Factor-alphaVasculitisInterleukin-1betaNitric OxideSodium Chloride, DietaryTumor Necrosis Factor-alpha

Identifiers

PMID28406245
PMCPMC5390251
OpenAlexW2606324864

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.