Evidence map›Paper›PMID 28406235›Full record

ArticleScientific reports2017

Physicochemical characterizations of functional hybrid liposomal nanocarriers formed using photo-sensitive lipids.

Sumit Kumar Pramanik, Patricia Losada-Pe Rez, Gunter Reekmans, Robert Carleer, Marc D'Olieslaeger, Dirk Vanderzande, Peter Adriaensens, Anitha Ethirajan

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Artificial exosomes for translational nanomedicine.Journal of nanobiotechnology · 2021
    Review
  6. Article
  7. Article
  8. A biomimetic nanoparticle-enabled toxoid vaccine against melittin.International journal of nanomedicine · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Sumit Kumar PramanikInstitute for Materials Research (IMO), Hasselt University, Wetenschapspark 1 and Agoralaan D, 3590 Diepenbeek, Belgium.
Patricia Losada-Pe RezInstitute for Materials Research (IMO), Hasselt University, Wetenschapspark 1 and Agoralaan D, 3590 Diepenbeek, Belgium.
Gunter ReekmansInstitute for Materials Research (IMO), Hasselt University, Wetenschapspark 1 and Agoralaan D, 3590 Diepenbeek, Belgium.
Robert CarleerInstitute for Materials Research (IMO), Hasselt University, Wetenschapspark 1 and Agoralaan D, 3590 Diepenbeek, Belgium.
Marc D'OlieslaegerInstitute for Materials Research (IMO), Hasselt University, Wetenschapspark 1 and Agoralaan D, 3590 Diepenbeek, Belgium.
Dirk VanderzandeInstitute for Materials Research (IMO), Hasselt University, Wetenschapspark 1 and Agoralaan D, 3590 Diepenbeek, Belgium.
Peter AdriaensensInstitute for Materials Research (IMO), Hasselt University, Wetenschapspark 1 and Agoralaan D, 3590 Diepenbeek, Belgium.
Anitha EthirajanInstitute for Materials Research (IMO), Hasselt University, Wetenschapspark 1 and Agoralaan D, 3590 Diepenbeek, Belgium.
IMEC · BEHasselt University · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With recent advances in the field of diagnostics and theranostics, liposomal technology has secured a fortified position as a potential nanocarrier. Specifically, radiation/photo-sensitive liposomes containing photo-polymerizable cross-linking lipids are intriguing as they can impart the vesicles with highly interesting properties such as response to stimulus and improved shell stability. In this work, 1,2-bis(10,12-tricosadiynoyl)-sn-glycero-3-phosphoethanolamine (DTPE) is used as a photo-polymerizable lipid to form functional hybrid-liposomes as it can form intermolecular cross-linking through the diacetylenic groups. Hybrid-liposomes were formulated using mixtures of DTPE and saturated lipids of different chain lengths (dipalmitoylphosphatidylcholine (DPPC) and dimirystoilphosphatidylcholine (DMPC)) at different molar ratios. The physico-chemical characteristics of the liposomes has been studied before and after UV irradiation using a combination of techniques: DSC, QCM-D and solid-state NMR. The results signify the importance of a subtle modification in alkyl chain length on the phase behavior of the hybrid-liposomes and on the degree of crosslinking in the shell.

Indexed as

Chemical PhenomenaDrug CarriersLightLipidsLiposomesMagnetic Resonance SpectroscopyMolecular StructureNanoparticlesPhotochemical ProcessesTheranostic NanomedicineThermogravimetryDrug CarriersLipidsLiposomes

Identifiers

PMID28406235
PMCPMC5390264
OpenAlexW2606822674

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.