ArticleNature communications2017
Implantable batteryless device for on-demand and pulsatile insulin administration.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Nanoparticle-Enabled Biomaterials for Controlled Drug Delivery in Implantable and Wearable Devices.International journal of molecular sciences · 2026Review
- An implantable dual-chamber capsule with three release modes for site-specific delivery and enhanced therapeutic efficacy.iScience · 2026Article
- Article
- Soft bioelectronics for wireless drug delivery: programmable, minimally invasive and closed-loop therapeutics.npj soft matter · 2026Review
- A Mini-Patch Magnetic Insulin Pump for Enhanced Delivery Resolution and Accuracy.Advanced intelligent systems (Weinheim an der Bergstrasse, Germany) · 2026Article
- Toward Wireless Implantable Robotic Systems Driven by Magnetic Field for Personalized Therapy.Advanced robotics research · 2025Article
- Dual-phoretic wireless device for directionally oriented and carrier-free targeted drug delivery.Science advances · 2025Article
- Advancements in Passive Wireless Sensing Systems in Monitoring Harsh Environment and Healthcare Applications.Nano-micro letters · 2025Review
- Miniaturized therapeutic systems for ultrasound-modulated drug delivery to the central and peripheral nervous system.Advanced drug delivery reviews · 2024Review
- Advances in Wireless, Batteryless, Implantable Electronics for Real-Time, Continuous Physiological Monitoring.Nano-micro letters · 2023Review
- Implantable device with magnetically rotating disk for needle-free administrations of emergency drug.Bioengineering & translational medicine · 2023Article
- Characterization of Cyclic Olefin Copolymers for Insulin Reservoir in an Artificial Pancreas.Journal of functional biomaterials · 2023Article
- Implantable device actuated by manual button clicks for noninvasive self-drug administration.Bioengineering & translational medicine · 2023Article
- Recent advances in mechanical force-responsive drug delivery systems.Nanoscale advances · 2022Review
- Microelectromechanical Systems Based on Magnetic Polymer Films.Micromachines · 2022Review
- Potentials of Neuropeptides as Therapeutic Agents for Neurological Diseases.Biomedicines · 2022Review
- Photomechanical Polymer Nanocomposites for Drug Delivery Devices.Molecules (Basel, Switzerland) · 2021Article
- Stability andRSC advances · 2021Article
- Implantable biorobotic organs.APL bioengineering · 2020Article
- Wirelessly Controlled Implantable System for On-demand and Pulsatile Insulin Administration.Scientific reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Many implantable systems have been designed for long-term, pulsatile delivery of insulin, but the lifetime of these devices is limited by the need for battery replacement and consequent replacement surgery. Here we propose a batteryless, fully implantable insulin pump that can be actuated by a magnetic field. The pump is prepared by simple-assembly of magnets and constituent units and comprises a drug reservoir and actuator equipped with a plunger and barrel, each assembled with a magnet. The plunger moves to noninvasively infuse insulin only when a magnetic field is applied on the exterior surface of the body. Here we show that the dose is easily controlled by varying the number of magnet applications. Also, pump implantation in diabetic rats results in profiles of insulin concentration and decreased blood glucose levels similar to those observed in rats treated with conventional subcutaneous insulin injections.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.