ArticleScientific reports2017
Spicule formation in calcareous sponges: Coordinated expression of biomineralization genes and spicule-type specific genes.
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 36 citations in OpenAlex.
- Independent origins of spicules reconcile paleontological and molecular evidence of sponge evolutionary history.Science advances · 2026Article
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- Chemical Investigation of the Calcareous Marine SpongeMarine drugs · 2024Article
- Silica-associated proteins from hexactinellid sponges support an alternative evolutionary scenario for biomineralization in Porifera.Nature communications · 2024Article
- Crystallographic control of the fabrication of an extremely sophisticated shell surface microornament in the glass scallop Catillopecten.Scientific reports · 2022Article
- The Evolution of Biomineralization through the Co-Option of Organic Scaffold Forming Networks.Cells · 2022Review
- Calcite Nanotuned Chitinous Skeletons of GiantInternational journal of molecular sciences · 2021Article
- Genes encoding putative bicarbonate transporters as a missing molecular link between molt and mineralization in crustaceans.Scientific reports · 2021Article
- Carbonic Anhydrases: An Ancient Tool in Calcareous Sponge Biomineralization.Frontiers in genetics · 2021Article
- In Situ Hybridization Techniques in the Homoscleromorph Sponge Oscarella lobularis.Methods in molecular biology (Clifton, N.J.) · 2021Article
- Naked chancelloriids from the lower Cambrian of China show evidence for sponge-type growth.Proceedings. Biological sciences · 2018Article
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Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The ability to form mineral structures under biological control is widespread among animals. In several species, specific proteins have been shown to be involved in biomineralization, but it is uncertain how they influence the shape of the growing biomineral and the resulting skeleton. Calcareous sponges are the only sponges that form calcitic spicules, which, based on the number of rays (actines) are distinguished in diactines, triactines and tetractines. Each actine is formed by only two cells, called sclerocytes. Little is known about biomineralization proteins in calcareous sponges, other than that specific carbonic anhydrases (CAs) have been identified, and that uncharacterized Asx-rich proteins have been isolated from calcitic spicules. By RNA-Seq and RNA in situ hybridization (ISH), we identified five additional biomineralization genes in Sycon ciliatum: two bicarbonate transporters (BCTs) and three Asx-rich extracellular matrix proteins (ARPs). We show that these biomineralization genes are expressed in a coordinated pattern during spicule formation. Furthermore, two of the ARPs are spicule-type specific for triactines and tetractines (ARP1 or SciTriactinin) or diactines (ARP2 or SciDiactinin). Our results suggest that spicule formation is controlled by defined temporal and spatial expression of spicule-type specific sets of biomineralization genes.
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