Evidence map›Paper›PMID 28405820›Full record

ArticleEuropean journal of nutrition2018

Higher dietary acid load is associated with a higher prevalence of frailty, particularly slowness/weakness and low physical activity, in elderly Japanese women.

Yuki Kataya, Kentaro Murakami, Satomi Kobayashi, Hitomi Suga, Satoshi Sasaki, Three-generation Study of Women on Diets and Health Study Group

Abstract read
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In one paragraph

Article in European journal of nutrition, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  9. Citrate-based dietary alkali supplements available in Germany: an overview.Journal of pharmaceutical health care and sciences · 2024
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  17. The therapeutic importance of acid-base balance.Biochemical pharmacology · 2021
    Review
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yuki KatayaDepartment of Nutrition, School of Human Cultures, University of Shiga Prefecture, Shiga, Japan.
Kentaro MurakamiInterfaculty Initiative in Information Studies, University of Tokyo, Tokyo, 113 0033, Japan. kenmrkm@m.u-tokyo.ac.jp.
Satomi KobayashiDepartment of Social and Preventive Epidemiology, School of Public Health, University of Tokyo, Tokyo, Japan.
Hitomi SugaDepartment of Social and Preventive Epidemiology, Graduated School of Medicine, University of Tokyo, Tokyo, Japan.
Satoshi SasakiDepartment of Social and Preventive Epidemiology, School of Public Health, University of Tokyo, Tokyo, Japan.
Three-generation Study of Women on Diets and Health Study Group

Funding

Japan Society for the Promotion of Science 22240077Ministry of Education, Culture, Sports, Science and Technology of Japan 15K16213
6 · The paper itself

Abstract

objectiveEpidemiologic evidence on the potential effects of dietary acid load on frailty is lacking. This cross-sectional study examined the association between dietary acid load and frailty.

methodsThis study was based on self-reported data obtained from 2176 Japanese women aged 65-94 years. Dietary acid load was characterized as potential renal acid load (PRAL) and net endogenous acid production (NEAP), based on information on nutrient intake, obtained from a validated brief diet history questionnaire. Frailty score (0-5) was defined as the sum of slowness/weakness (two points), exhaustion (one point), low physical activity (one point), and unintentional weight loss (one point). A score of ≥3 was classified as indicating frailty.

resultsThe prevalence of frailty was 17.9%. After adjustment for potential confounding factors, higher PRAL and NEAP were associated with a higher prevalence of frailty. Adjusted OR (95% CI) for frailty in the highest compared to the lowest quintiles was 1.59 (1.08, 2.34) for PRAL (P for trend = 0.048) and 1.42 (0.98, 2.06) for NEAP (P for trend = 0.03). PRAL and NEAP also showed positive associations with the prevalence of slowness/weakness and low physical activity (all P for trend ≤0.03). PRAL (but not NEAP) was positively associated with the prevalence of exhaustion (P for trend = 0.04). There was no association for unintentional weight loss.

conclusionsDietary acid load was positively associated with the prevalence of frailty, particularly slowness/weakness and low physical activity, in elderly Japanese women.

Indexed as

DietAgedAged, 80 and overAsian PeopleCross-Sectional StudiesDietary FatsExerciseFemaleFrailtyHumansJapanNutrition AssessmentPrevalenceDietary FatsElderly Japanese womenEpidemiologyFrailtyNet endogenous acid productionPotential renal acid load

Identifiers

PMID28405820

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.