Evidence map›Paper›PMID 28405805›Full record

ArticleThe journal of physiological sciences : JPS2018

A rotating cerium anode X-ray system allows visualization of intramural coronary vessels after cardiac stem cell therapy for myocardial infarction.

Chiharu Tanaka, Toru Hosoda, Yoshimori Ikeya, Yoshiro Shinozaki, Kikue Todoroki, Toru Shizuma, Takashi Shiraishi, Naoto Fukuyama, Toshihiko Ueda, Hidezo Mori

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The journal of physiological sciences : JPS, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 93% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Chiharu TanakaDepartment of Cardiovascular Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. chitty@is.icc.u-tokai.ac.jp.
Toru HosodaTokai University Institute of Innovative Science and Technology, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
Yoshimori IkeyaDepartment of Physiology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
Yoshiro ShinozakiSupport Center for Medical Research and Education, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
Kikue TodorokiDepartment of Physiology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
Toru ShizumaDepartment of Physiology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
Takashi ShiraishiNHK Engineering Services, Inc., Tokyo, Japan.
Naoto FukuyamaDepartment of Physiology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
Toshihiko UedaDepartment of Cardiovascular Surgery, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan.
Hidezo MoriDepartment of Physiology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, 259-1193, Japan. coronary@is.icc.u-tokai.ac.jp.
Tokai University · JPAdvanced Engineering Services (Japan) · JP

Funding

Grant-in-Aid for Young Scientists B 25861233Grants-in-Aid for Scientific Research B 20390336Grants-in-Aid from The Cardiovascular Research Fund, Tokyo, Japan H24-06-01Health and Labour Sciences Research Grant 200624005AThe Research Funding for Longevity Sciences from National Center for Geriatrics and Gerontology 22-5
6 · The paper itself

Abstract

Conventional angiography is insufficient for evaluating the therapeutic effect of cardiac regeneration therapy. A microangiographic X-ray system using a cerium anode was developed. Cerium has a characteristic X-ray with a peak at 34.6 keV, which allows visualization of tiny amounts of iodine. The performance of the cerium anode X-ray system was evaluated in two excised normal canine hearts and in excised ischemic canine hearts treated with c-kit-positive cardiac stem cells (5 canines) or without cells (5 control canines). In the normal canines, branches penetrating from the left anterior descending artery into the myocardium were visualized, down to third-order branches. In just the treated hearts treated with stem cells, small vessels characterized by irregular vessel walls were observed. The cerium anode X-ray system allowed visualization of microvessels in excised ischemic canine hearts, and may evaluate the effect of cardiac stem cell therapy.

Indexed as

AnimalsCeriumCoronary VesselsDisease Models, AnimalDogsHeartMyocardial InfarctionStem Cell TransplantationX-RaysCeriumCanine modelsCerium anodeC-kit-positive cardiac stem cellsMicroangiographyMyocardial infarction

Identifiers

PMID28405805
PMCPMC10717793
OpenAlexW2606317772

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.