ArticlePflugers Archiv : European journal of physiology2017
Urine exosomes from healthy and hypertensive pregnancies display elevated level of α-subunit and cleaved α- and γ-subunits of the epithelial sodium channel-ENaC.
Article in Pflugers Archiv : European journal of physiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 33 citations in OpenAlex.
- Renin-Angiotensin-Aldosterone Profiles in Pregnant Women With Chronic Hypertension.Hypertension (Dallas, Tex. : 1979) · 2018Trial
- Exosomal Biomarkers: A Comprehensive Overview of Diagnostic and Prognostic Applications in Malignant and Non-Malignant Disorders.Biomolecules · 2025Review
- ENaCγ in Urinary Extracellular Vesicles as an Indicator of MR Signaling in Primary Aldosteronism.Hypertension (Dallas, Tex. : 1979) · 2024Article
- Urinary extracellular vesicles and tubular transport.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023Review
- The Epithelial Sodium Channel-An Underestimated Drug Target.International journal of molecular sciences · 2023Review
- Renal CD81 interacts with sodium potassium 2 chloride cotransporter and sodium chloride cotransporter in rats with lipopolysaccharide-induced preeclampsia.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2023Article
- Lipid Profiles of Urinary Extracellular Vesicles Released during the Inactive and Active Phases of Aged Male Mice with Spontaneous Hypertension.International journal of molecular sciences · 2022Article
- Research advances and challenges in tissue-derived extracellular vesicles.Frontiers in molecular biosciences · 2022Review
- Downregulation of Cullin 3 Ligase Signaling Pathways Contributes to Hypertension in Preeclampsia.Frontiers in cardiovascular medicine · 2021Article
- Time course of renal sodium transport in the pregnant rat.Current research in physiology · 2021Article
- Elevated Plasmin(ogen) as a Common Risk Factor for COVID-19 Susceptibility.Physiological reviews · 2020Review
- Extracellular vesicles in normal pregnancy and pregnancy-related diseases.Journal of cellular and molecular medicine · 2020Review
- The Role(s) of Eicosanoids and Exosomes in Human Parturition.Frontiers in physiology · 2020Review
- Regulating ENaC's gate.American journal of physiology. Cell physiology · 2020Review
- The epithelial NaPflugers Archiv : European journal of physiology · 2019Article
- Release of urinary aquaporin-2-bearing extracellular vesicles is decreased in pregnant Japanese Black cattle.The Journal of veterinary medical science · 2019Article
- Physiological and Molecular Responses to Altered Sodium Intake in Rat Pregnancy.Journal of the American Heart Association · 2018Article
- Epithelial NaAnnual review of physiology · 2018Review
- Article
- Urinary Exosomes and Their Cargo: Potential Biomarkers for Mineralocorticoid Arterial Hypertension?Frontiers in endocrinology · 2017Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
Abstract
Preeclampsia is characterized by hypertension, proteinuria, suppression of plasma renin-angiotensin-aldosterone, and impaired urine sodium excretion. Aberrantly filtered plasmin in urine may activate proteolytically the γ-subunit of the epithelial sodium channel (ENaC) and promote Na
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.