Evidence map›Paper›PMID 28405773›Full record

ArticleAnnals of biomedical engineering2017

Failure and Fatigue Properties of Immature Human and Porcine Parasagittal Bridging Veins.

Stephanie A Pasquesi, Susan S Margulies

Open access · greenAbstract read
In one paragraph

Article in Annals of biomedical engineering, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Injury Metrics for Assessing the Risk of Acute Subdural Hematoma in Traumatic Events.International journal of environmental research and public health · 2021
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Stress-Relaxation and Cyclic Behavior of Human Carotid Plaque Tissue.Frontiers in bioengineering and biotechnology · 2020
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Stephanie A PasquesiDepartment of Bioengineering, University of Pennsylvania, 240 Skirkanich Hall, 210 South 33rd Street, Philadelphia, PA, 19104-6321, USA.ORCID 0000-0002-3615-7902
Susan S MarguliesDepartment of Bioengineering, University of Pennsylvania, 240 Skirkanich Hall, 210 South 33rd Street, Philadelphia, PA, 19104-6321, USA. margulie@seas.upenn.edu.
University of Pennsylvania · US

Funding

Biomechanics of Pediatric Head InjuryR01NS039679 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI MARGULIES, SUSAN SHEPS · 2001 to 2011
$5.0M
PRECLINICAL CYCLOSPORIN A THERAPY TRIALS FOR PEDIATRIC TBIU01NS069545 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI DUHAIME, ANN-CHRISTINE, MARGULIES, SUSAN SHEPS · 2011 to 2017
$3.5M
Traumatic Bridging Vein Failure in InfantsR21HD078842 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI MARGULIES, SUSAN SHEPS · 2014 to 2015
$424k
NICHD NIH HHS R21 HD078842NINDS NIH HHS R01 NS039679NINDS NIH HHS U01 NS069545
6 · The paper itself

Abstract

Tearing of the parasagittal bridging veins (BVs) is thought to be a source of extra-axial hemorrhage (EAH) associated with abusive traumatic brain injuries (TBIs) in children. However, the pediatric BV mechanical properties are unknown. We subjected porcine adult, porcine newborn, and human infant BVs to either a low rate pull to failure, a high rate pull to failure, or 30 s of cyclic loading followed by a pull to failure. An additional subset of human infant BVs was examined for viscoelastic recovery between two cycling episodes. We found that human infant BVs are stronger than porcine BVs, and BV mechanical properties are rate dependent, but not age dependent. Successive cyclic loading to a uniform level of stretch softened BVs with decaying peak stresses, and shifted their stress-stretch relationship. These data are critical in understanding BV tissue behavior in accidental and abusive trauma scenarios, which in turn may clarify circumstances that may be injurious to young children.

Indexed as

Models, CardiovascularAgingAnimalsAnimals, NewbornCadaverCerebral VeinsComputer SimulationElastic ModulusHumansInfantInfant, NewbornIn Vitro TechniquesSpecies SpecificityStress, MechanicalSwineTensile StrengthAbusive head traumaBrain injuryChild abuseHemorrhageMechanical propertiesPediatric trauma

Identifiers

PMID28405773
PMCPMC5529232
OpenAlexW2607352135

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.