Evidence map›Paper›PMID 28405730›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2017

Sex-related variations in cortical and trabecular bone of the femoral neck in an elderly Chinese population.

L Wang, X G Cheng, Y B Su, K Brown, L Xu, K Li, C X Zhang, Y Zhang, Y Y Duanmu, X B Wu and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

L WangDepartment of Radiology, Beijing Jishuitan Hospital, Xicheng District, Beijing, China.
X G ChengDepartment of Radiology, Beijing Jishuitan Hospital, Xicheng District, Beijing, China. xiao65@263.net.
Y B SuDepartment of Radiology, Beijing Jishuitan Hospital, Xicheng District, Beijing, China.
K BrownMindways Software, Austin, TX, USA.
L XuDepartment of Radiology, Beijing Jishuitan Hospital, Xicheng District, Beijing, China.
K LiDepartment of Radiology, Beijing Jishuitan Hospital, Xicheng District, Beijing, China.
C X ZhangDepartment of Radiology, Beijing Jishuitan Hospital, Xicheng District, Beijing, China.
Y ZhangDepartment of Radiology, Beijing Jishuitan Hospital, Xicheng District, Beijing, China.
Y Y DuanmuDepartment of Radiology, Beijing Jishuitan Hospital, Xicheng District, Beijing, China.
X B WuDepartment of Traumatology and Orthopedic Surgery, Beijing Jishuitan Hospital, Xicheng District, Beijing, China.
M Y WangDepartment of Traumatology and Orthopedic Surgery, Beijing Jishuitan Hospital, Xicheng District, Beijing, China.
Beijing Jishuitan Hospital · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quantitative computed tomography (QCT) was used to investigate sex-related variations in cortical and trabecular bone of the femoral neck. Cortical bone thickness of women in the superior quadrant was thinner than that of men, and the cortex in all four quadrants was negatively associated with age in women.

introductionThis cross-sectional study aimed to investigate sex-related similarities and differences in femoral neck structure in an elderly Chinese population by QCT bone investigational toolkit (BIT) analysis.

methodsThis study included 207 male (67.9 ± 7.7 years; range, 55-87 years) and 400 female subjects (68.0 ± 8.7 years; range, 55-96 years). BIT module was used to measure cortical and trabecular bone in anatomic quadrants of the femoral neck. Measurements of cortical thickness (Ct.Th), cortical vBMD (Ct.vBMD), trabecular vBMD (Tb.vBMD), and integral vBMD (It.vBMD) at the femoral neck were determined in four anatomical sectors.

resultsThe greatest difference between sexes, after adjusting for age, height, and weight, was in Ct.Th of Quadrant Supero-anterior (SA), which was 27.4% lower in women (p<0.001). Ct.Th of Quadrant Supero-posterior (SP) was 15.1% lower in women (p = 0.027). Ct.Th and Tb.vBMD in all four quadrants appeared to be negatively associated with age in females, whereas no significant relationship was observed in males, except Ct.Th of Quadrant SP.

conclusionsThe superior femoral neck geometry between males and females was significantly different, even after adjustment for body size and age, and the sub-regional cortical and trabecular bone negatively age-related changes in women indicated that women apparently have a more vulnerable geometrical outcome with age for fractures than men.

Indexed as

Sex CharacteristicsAgedAged, 80 and overAgingBone DensityCancellous BoneCortical BoneCross-Sectional StudiesFemaleFemur NeckHumansMaleMiddle AgedTomography, X-Ray ComputedCortical boneFemoral neckQCTSexTrabecular bone

Identifiers

PMID28405730
OpenAlexW2606804192

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.