Evidence map›Paper›PMID 28405442›Full record

ReviewPorcine health management2016

Spray dried plasma as an alternative to antibiotics in piglet feeds, mode of action and biosafety.

Anna Pérez-Bosque, Javier Polo, David Torrallardona

Open access · goldAbstract readReview
In one paragraph

Review in Porcine health management, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 109 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Use of Different Synbiotic Strategies to Improve Gut Health in Dogs.Animals : an open access journal from MDPI · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Effect of Oral Administration withAnimals : an open access journal from MDPI · 2023
    Article
  16. Spray-Dried Animal Plasma as a Multifaceted Ingredient in Pet Food.Animals : an open access journal from MDPI · 2023
    Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Anna Pérez-BosqueGrup de Fisiologia digestiva i adaptacions nutricionals, Departament de Bioquímica i Fisiologia, Facultat de Farmàcia i Ciències de l'Alimentació, Institut de Recerca en Nutrició i Seguretat Alimentària, Universitat de Barcelona (UB), Barcelona, Spain.
Javier PoloAPC Europe, S.A., Granollers, Spain.
David TorrallardonaIRTA, Animal Nutrition and Welfare, Mas de Bover, Ctra. Reus-El Morell, km. 3.8, E-43120 Constantí, Tarragona, Spain.
APC Europe (Spain) · ESInstitute for Research and Technology in Food and Agriculture · ESUniversitat de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of growth promoting and therapeutic antibiotics in piglet feed has been a concerning subject over the last few decades because of the risk of generating antimicrobial resistance that could be transferred to humans. As a result, many products have been proposed as potential alternatives to the use of antibiotics, and among these, spray dried plasma is considered one of the most promising. However, there have been concerns about its biosafety, particularly during periods of emergence or re-emergence of swine diseases in different regions of the world, such as the recent porcine epidemic diarrhea virus outbreak in North America. The objectives of this paper are to review recent publications about the use of spray dried plasma as an alternative to antibiotics in weaned pig diets, the possible mechanisms of action of spray dried plasma, and the existing evidence related to the biosafety of spray dried animal plasma. Particular attention is given to studies in which spray dried plasma has been directly compared to antibiotics or other alternative antimicrobial products. Several studies on the possible modes of action for spray dried plasma, such as preservation of gut barrier function or modulation of the immune response, are also reviewed. Finally, the paper focuses on the review of the existing studies on the risks of disease transmission with the use of spray dried plasma from porcine origin. Overall, spray dried plasma is a promising alternative to in-feed antimicrobials for piglets, particularly during the early stages of the post-weaning phase. Additionally, there is enough evidence to support that commercial spray dried porcine plasma is a safe product for pigs.

Indexed as

Antibiotic replacementAntibioticsBiosafetyGut barrier functionImmunomodulationPigletsSpray dried plasmaSpray dried porcine plasma

Identifiers

PMID28405442
PMCPMC5382520
OpenAlexW2437169968

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.