Evidence map›Paper›PMID 28405313›Full record

ArticleJournal of animal science and biotechnology2017

Artificial rearing influences the morphology, permeability and redox state of the gastrointestinal tract of low and normal birth weight piglets.

Hans Vergauwen, Jeroen Degroote, Sara Prims, Wei Wang, Erik Fransen, Stefaan De Smet, Christophe Casteleyn, Steven Van Cruchten, Joris Michiels, Chris Van Ginneken

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of animal science and biotechnology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hans Vergauwen *Laboratory of Applied Veterinary Morphology, Department of Veterinary Sciences, Faculty of Biomedical, Pharmaceutical and Veterinary Sciences, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, D.U.015, 2610 Wilrijk, Belgium.
Jeroen Degroote *Department of Applied Biosciences, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
Sara PrimsLaboratory of Applied Veterinary Morphology, Department of Veterinary Sciences, Faculty of Biomedical, Pharmaceutical and Veterinary Sciences, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, D.U.015, 2610 Wilrijk, Belgium.
Wei WangDepartment of Applied Biosciences, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
Erik FransenStatUa Center for Statistics, University of Antwerp, Antwerp, Belgium.
Stefaan De SmetLaboratory for Animal Nutrition and Animal Product Quality (LANUPRO), Department of Animal Production, Faculty of Bioscience Engineering, Ghent University, Melle, Belgium.
Christophe CasteleynLaboratory of Applied Veterinary Morphology, Department of Veterinary Sciences, Faculty of Biomedical, Pharmaceutical and Veterinary Sciences, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, D.U.015, 2610 Wilrijk, Belgium.
Steven Van CruchtenLaboratory of Applied Veterinary Morphology, Department of Veterinary Sciences, Faculty of Biomedical, Pharmaceutical and Veterinary Sciences, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, D.U.015, 2610 Wilrijk, Belgium.
Joris MichielsDepartment of Applied Biosciences, Faculty of Bioscience Engineering, Ghent University, Ghent, Belgium.
Chris Van GinnekenLaboratory of Applied Veterinary Morphology, Department of Veterinary Sciences, Faculty of Biomedical, Pharmaceutical and Veterinary Sciences, University of Antwerp, Campus Drie Eiken, Universiteitsplein 1, D.U.015, 2610 Wilrijk, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn this study the physiological implications of artificial rearing were investigated. Low (LBW) and normal birth weight (NBW) piglets were compared as they might react differently to stressors caused by artificial rearing. In total, 42 pairs of LBW and NBW piglets from 16 litters suckled the sow until d19 of age or were artificially reared starting at d3 until d19 of age. Blood and tissue samples that were collected after euthanasia at 0, 3, 5, 8 and 19 d of age. Histology, ELISA, and Ussing chamber analysis were used to study proximal and distal small intestine histo-morphology, proliferation, apoptosis, tight junction protein expression, and permeability. Furthermore, small intestine, liver and systemic redox parameters (GSH, GSSG, GSH-Px and MDA) were investigated using HPLC.

resultsLBW and NBW artificially reared piglets weighed respectively 40 and 33% more than LBW and NBW sow-reared piglets at d19 (

conclusionThe results suggest that artificial rearing altered the morphology, permeability and redox state without compromising piglet performance. The observed effects were not depending on birth weight.

Indexed as

Milk replacerOxidative stressSmall intestineSuckling periodTight junction proteins

Identifiers

PMID28405313
PMCPMC5385054

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.