Evidence map›Paper›PMID 28405187›Full record

ArticleFrontiers in aging neuroscience2017

Identification of Cerebral Metal Ion Imbalance in the Brain of Aging

Nady Braidy, Anne Poljak, Chris Marjo, Helen Rutlidge, Anne Rich, Bat-Erdene Jugder, Tharusha Jayasena, Nibaldo C Inestrosa, Perminder S Sachdev

RetractedErratum issuedOpen access · goldAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in aging neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
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  6. NEUROTOXICITY OF METAL MIXTURES.Advances in neurotoxicology · 2021
    Article
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  8. Article
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  10. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Nady BraidyCentre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South Wales Sydney, NSW, Australia.
Anne PoljakCentre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South WalesSydney, NSW, Australia; Mark Wainwright Analytical Centre, University of New South WalesSydney, NSW, Australia; School of Medical Sciences, Faculty of Medicine, University of New South WalesSydney, NSW, Australia.
Chris MarjoMark Wainwright Analytical Centre, University of New South Wales Sydney, NSW, Australia.
Helen RutlidgeMark Wainwright Analytical Centre, University of New South Wales Sydney, NSW, Australia.
Anne RichMark Wainwright Analytical Centre, University of New South Wales Sydney, NSW, Australia.
Bat-Erdene JugderSchool of Biotechnology and Biomolecular Sciences, Faculty of Science, University of New South Wales Sydney, NSW, Australia.
Tharusha JayasenaCentre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South Wales Sydney, NSW, Australia.
Nibaldo C InestrosaCentre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South WalesSydney, NSW, Australia; Centre for Ageing and Regeneration, Faculty of Biological Sciences, Pontifical Catholic University of ChileSantiago, Chile.
Perminder S SachdevCentre for Healthy Brain Ageing, School of Psychiatry, Faculty of Medicine, University of New South WalesSydney, NSW, Australia; Neuropsychiatric Institute, Euroa Centre, Prince of Wales HospitalSydney, NSW, Australia.
UNSW Sydney · AUPontificia Universidad Católica de Chile · CL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The accumulation of redox-active transition metals in the brain and metal dyshomeostasis are thought to be associated with the etiology and pathogenesis of several neurodegenerative diseases, and Alzheimer's disease (AD) in particular. As well, distinct biometal imaging and role of metal uptake transporters are central to understanding AD pathogenesis and aging but remain elusive, due inappropriate detection methods. We therefore hypothesized that

Indexed as

Alzheimer’s diseasebioimagingLA-ICPMSmetalsOctodon degus

Identifiers

PMID28405187
PMCPMC5370394
OpenAlexW2598291967

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.