Evidence map›Paper›PMID 28405060›Full record

ArticleProceedings (Baylor University. Medical Center)2017

Personalized treatment of heart failure with biomarker guidance using a novel disease severity score.

Anupama Vasudevan, Hourossadat Hashemi Jazi, Jane I Won, Timothy Ball, Gautam R Patankar, Syed A Sarmast, Hyun Joon Shin, Peter A McCullough

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Proceedings (Baylor University. Medical Center), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.9field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Anupama VasudevanBaylor Heart and Vascular Institute, Dallas, Texas (Vasudevan, Won); Texas A&M Health Science Center College of Medicine, Dallas Campus, Dallas, Texas (Vasudevan, Won, McCullough); Baylor Research Institute, Dallas, Texas (Vasudevan, Won); Baylor University Medical Center, Dallas, Texas (Jazi, Ball, Patankar, Sarmast, McCullough); Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas (Ball, Won, Patankar, Sarmast, McCullough); Division of Aging, Department of Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts (Shin); Division of Cardiology, Department of Medicine, VA Boston Health Care System, Boston, Massachusetts (Shin); and The Heart Hospital Baylor Plano, Plano, Texas (McCullough).
Hourossadat Hashemi JaziBaylor Heart and Vascular Institute, Dallas, Texas (Vasudevan, Won); Texas A&M Health Science Center College of Medicine, Dallas Campus, Dallas, Texas (Vasudevan, Won, McCullough); Baylor Research Institute, Dallas, Texas (Vasudevan, Won); Baylor University Medical Center, Dallas, Texas (Jazi, Ball, Patankar, Sarmast, McCullough); Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas (Ball, Won, Patankar, Sarmast, McCullough); Division of Aging, Department of Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts (Shin); Division of Cardiology, Department of Medicine, VA Boston Health Care System, Boston, Massachusetts (Shin); and The Heart Hospital Baylor Plano, Plano, Texas (McCullough).
Jane I WonBaylor Heart and Vascular Institute, Dallas, Texas (Vasudevan, Won); Texas A&M Health Science Center College of Medicine, Dallas Campus, Dallas, Texas (Vasudevan, Won, McCullough); Baylor Research Institute, Dallas, Texas (Vasudevan, Won); Baylor University Medical Center, Dallas, Texas (Jazi, Ball, Patankar, Sarmast, McCullough); Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas (Ball, Won, Patankar, Sarmast, McCullough); Division of Aging, Department of Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts (Shin); Division of Cardiology, Department of Medicine, VA Boston Health Care System, Boston, Massachusetts (Shin); and The Heart Hospital Baylor Plano, Plano, Texas (McCullough).
Timothy BallBaylor Heart and Vascular Institute, Dallas, Texas (Vasudevan, Won); Texas A&M Health Science Center College of Medicine, Dallas Campus, Dallas, Texas (Vasudevan, Won, McCullough); Baylor Research Institute, Dallas, Texas (Vasudevan, Won); Baylor University Medical Center, Dallas, Texas (Jazi, Ball, Patankar, Sarmast, McCullough); Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas (Ball, Won, Patankar, Sarmast, McCullough); Division of Aging, Department of Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts (Shin); Division of Cardiology, Department of Medicine, VA Boston Health Care System, Boston, Massachusetts (Shin); and The Heart Hospital Baylor Plano, Plano, Texas (McCullough).
Gautam R PatankarBaylor Heart and Vascular Institute, Dallas, Texas (Vasudevan, Won); Texas A&M Health Science Center College of Medicine, Dallas Campus, Dallas, Texas (Vasudevan, Won, McCullough); Baylor Research Institute, Dallas, Texas (Vasudevan, Won); Baylor University Medical Center, Dallas, Texas (Jazi, Ball, Patankar, Sarmast, McCullough); Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas (Ball, Won, Patankar, Sarmast, McCullough); Division of Aging, Department of Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts (Shin); Division of Cardiology, Department of Medicine, VA Boston Health Care System, Boston, Massachusetts (Shin); and The Heart Hospital Baylor Plano, Plano, Texas (McCullough).
Syed A SarmastBaylor Heart and Vascular Institute, Dallas, Texas (Vasudevan, Won); Texas A&M Health Science Center College of Medicine, Dallas Campus, Dallas, Texas (Vasudevan, Won, McCullough); Baylor Research Institute, Dallas, Texas (Vasudevan, Won); Baylor University Medical Center, Dallas, Texas (Jazi, Ball, Patankar, Sarmast, McCullough); Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas (Ball, Won, Patankar, Sarmast, McCullough); Division of Aging, Department of Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts (Shin); Division of Cardiology, Department of Medicine, VA Boston Health Care System, Boston, Massachusetts (Shin); and The Heart Hospital Baylor Plano, Plano, Texas (McCullough).
Hyun Joon ShinBaylor Heart and Vascular Institute, Dallas, Texas (Vasudevan, Won); Texas A&M Health Science Center College of Medicine, Dallas Campus, Dallas, Texas (Vasudevan, Won, McCullough); Baylor Research Institute, Dallas, Texas (Vasudevan, Won); Baylor University Medical Center, Dallas, Texas (Jazi, Ball, Patankar, Sarmast, McCullough); Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas (Ball, Won, Patankar, Sarmast, McCullough); Division of Aging, Department of Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts (Shin); Division of Cardiology, Department of Medicine, VA Boston Health Care System, Boston, Massachusetts (Shin); and The Heart Hospital Baylor Plano, Plano, Texas (McCullough).
Peter A McCulloughBaylor Heart and Vascular Institute, Dallas, Texas (Vasudevan, Won); Texas A&M Health Science Center College of Medicine, Dallas Campus, Dallas, Texas (Vasudevan, Won, McCullough); Baylor Research Institute, Dallas, Texas (Vasudevan, Won); Baylor University Medical Center, Dallas, Texas (Jazi, Ball, Patankar, Sarmast, McCullough); Baylor Jack and Jane Hamilton Heart and Vascular Hospital, Dallas, Texas (Ball, Won, Patankar, Sarmast, McCullough); Division of Aging, Department of Medicine, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts (Shin); Division of Cardiology, Department of Medicine, VA Boston Health Care System, Boston, Massachusetts (Shin); and The Heart Hospital Baylor Plano, Plano, Texas (McCullough).
Baylor Jack and Jane Hamilton Heart and Vascular Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We propose a novel Myocardial Injury Summary Score (MISS) integrating the 4 biomarkers suggested by the 2013 American College of Cardiology/American Heart Association guidelines for management of heart failure. In this case series, we examined 4 heart failure patients who received treatment guided by the biomarker results and 4 patients who received routine clinical management with no information about the biomarkers. Most of the patients receiving biomarker-guided management had medications adjusted based on the biomarker values, while no changes were recommended for patients in the biomarker-blinded category. This case series suggests that biomarker-guided therapy with serial biomarker values leads to timely therapeutic adjustment and that biomarker values as a composite score can be used effectively to measure the severity of heart failure.

Identifiers

PMID28405060
PMCPMC5349806
OpenAlexW2774114119

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.