Evidence map›Paper›PMID 28405017›Full record

ArticleImmunology and cell biology2017

Lectin pathway factors in patients suffering from juvenile idiopathic arthritis.

Katarzyna Kasperkiewicz, Łukasz Eppa, Anna S Świerzko, Marcin A Bartłomiejczyk, Zbigniew M Żuber, Katarzyna Siniewicz-Luzeńczyk, Elżbieta Mężyk, Misao Matsushita, Leokadia Bąk-Romaniszyn, Krzysztof Zeman and 2 more

Open access · bronzeAbstract read
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In one paragraph

Article in Immunology and cell biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.8field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Observational
  3. Article
  4. Polymorphisms of theFrontiers in immunology · 2021
    Article
  5. Article
  6. The Role ofJournal of immunology research · 2020
    Article
  7. Article
  8. Observational
  9. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 4 countries.

Katarzyna KasperkiewiczFaculty of Biology and Environmental Protection, Department of Microbiology, University of Silesia, Katowice, Poland.
Łukasz EppaLaboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland.
Anna S ŚwierzkoLaboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland.
Marcin A BartłomiejczykLaboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland.
Zbigniew M ŻuberDepartment of Rheumatology, St Louis Voivodeship Specialist Children's Hospital, Cracow, Poland.
Katarzyna Siniewicz-LuzeńczykDepartment of Paediatrics, Immunology and Nephrology, Polish Mother's Memorial Hospital Research Institute, Lodz, Poland.
Elżbieta MężykDepartment of Rheumatology, St Louis Voivodeship Specialist Children's Hospital, Cracow, Poland.
Misao MatsushitaDepartment of Applied Biochemistry, Tokai University, Hiratsuka-shi, Kanagawa, Japan.
Leokadia Bąk-RomaniszynDepartment of Nutrition in Digestive Tract Diseases, Medical University of Lodz, Lodz, Poland.
Krzysztof ZemanDepartment of Paediatrics, Immunology and Nephrology, Polish Mother's Memorial Hospital Research Institute, Lodz, Poland.
Mikael SkurnikResearch Programs Unit, Department of Bacteriology and Immunology, Medicum, Immunobiology, University of Helsinki, Helsinki, Finland.ORCID 0000-0001-8791-9260
Maciej CedzyńskiLaboratory of Immunobiology of Infections, Institute of Medical Biology, Polish Academy of Sciences, Lodz, Poland.
Polish Academy of Sciences · PLPolish Mother’s Memorial Hospital Research Institute · PLSt. Louis Children's Hospital · USInstitute for Medical Biology · PLMedical University of Lodz · PLTokai University · JPUniversity of Helsinki · FIUniversity of Silesia in Katowice · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Both complement activation and certain infections (including those with Yersinia sp.) may contribute to the pathogenesis of juvenile idiopathic arthritis (JIA). We investigated factors specific for the lectin pathway of complement: mannose-binding lectin (MBL), ficolins and MBL-associated serine protease-2 (MASP-2), in 144 patients and 98 controls. One hundred and six patients had oligoarticular disease and 38 had polyarticular disease. In 51 patients (out of 133 tested), Yersinia-reactive antibodies were found (JIA Ye

Indexed as

AdolescentAntibodies, BacterialArthritis, JuvenileChildChild, PreschoolComplement Pathway, Mannose-Binding LectinFicolinsGene FrequencyGenetic Predisposition to DiseaseGenotypeGlycoproteinsHumansInfantLectinsMaleMannose-Binding LectinAntibodies, BacterialFCN3 protein, humanFicolinsGlycoproteinsLectinsMannose-Binding LectinMannose-Binding Protein-Associated Serine ProteasesMASP2 protein, humanMBL2 protein, human

Identifiers

PMID28405017
OpenAlexW2607306198

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.