Evidence map›Paper›PMID 28404807›Full record

SynthesisNeurology2017

Body composition status and the risk of migraine: A meta-analysis.

Bizu Gelaye, Simona Sacco, Wendy J Brown, Haley L Nitchie, Raffaele Ornello, B Lee Peterlin

Abstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed, 3 pooled it
5.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed, 3 syntheses or guidelines pooled it, 112 citations in OpenAlex.

  1. Pooled it
  2. Migraine and sleep disorders: a systematic review.The journal of headache and pain · 2020
    Pooled it
  3. Pooled it
  4. Trial
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  9. Sex-specific considerations in migraine therapy.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026
    Review
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  11. Article
  12. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Bizu GelayeFrom the Harvard T.H. Chan School of Public Health (B.G.), Department of Epidemiology, Boston, MA; Department of Neurology (S.S., R.O.), University of L'Aquila, Italy; School of Human Movement and Nutrition Sciences (W.J.B.), University of Queensland, Brisbane, Australia; and Department of Neurology (H.L.N., B.L.P.), Johns Hopkins University School of Medicine, Baltimore, MD.
Simona SaccoFrom the Harvard T.H. Chan School of Public Health (B.G.), Department of Epidemiology, Boston, MA; Department of Neurology (S.S., R.O.), University of L'Aquila, Italy; School of Human Movement and Nutrition Sciences (W.J.B.), University of Queensland, Brisbane, Australia; and Department of Neurology (H.L.N., B.L.P.), Johns Hopkins University School of Medicine, Baltimore, MD.
Wendy J BrownFrom the Harvard T.H. Chan School of Public Health (B.G.), Department of Epidemiology, Boston, MA; Department of Neurology (S.S., R.O.), University of L'Aquila, Italy; School of Human Movement and Nutrition Sciences (W.J.B.), University of Queensland, Brisbane, Australia; and Department of Neurology (H.L.N., B.L.P.), Johns Hopkins University School of Medicine, Baltimore, MD.
Haley L NitchieFrom the Harvard T.H. Chan School of Public Health (B.G.), Department of Epidemiology, Boston, MA; Department of Neurology (S.S., R.O.), University of L'Aquila, Italy; School of Human Movement and Nutrition Sciences (W.J.B.), University of Queensland, Brisbane, Australia; and Department of Neurology (H.L.N., B.L.P.), Johns Hopkins University School of Medicine, Baltimore, MD.
Raffaele OrnelloFrom the Harvard T.H. Chan School of Public Health (B.G.), Department of Epidemiology, Boston, MA; Department of Neurology (S.S., R.O.), University of L'Aquila, Italy; School of Human Movement and Nutrition Sciences (W.J.B.), University of Queensland, Brisbane, Australia; and Department of Neurology (H.L.N., B.L.P.), Johns Hopkins University School of Medicine, Baltimore, MD.
B Lee PeterlinFrom the Harvard T.H. Chan School of Public Health (B.G.), Department of Epidemiology, Boston, MA; Department of Neurology (S.S., R.O.), University of L'Aquila, Italy; School of Human Movement and Nutrition Sciences (W.J.B.), University of Queensland, Brisbane, Australia; and Department of Neurology (H.L.N., B.L.P.), Johns Hopkins University School of Medicine, Baltimore, MD. lpeterlin@jhmi.edu.
University of L'Aquila · ITUniversity of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the association between migraine and body composition status as estimated based on body mass index and WHO physical status categories.

methodsSystematic electronic database searches were conducted for relevant studies. Two independent reviewers performed data extraction and quality appraisal. Odds ratios (OR) and confidence intervals (CI) were pooled using a random effects model. Significant values, weighted effect sizes, and tests of homogeneity of variance were calculated.

resultsA total of 12 studies, encompassing data from 288,981 unique participants, were included. The age- and sex-adjusted pooled risk of migraine in those with obesity was increased by 27% compared with those of normal weight (odds ratio [OR] 1.27; 95% confidence interval [CI] 1.16-1.37,

conclusionsThe current body of evidence shows that the risk of migraine is increased in obese and underweight individuals. Studies are needed to confirm whether interventions that modify obesity status decrease the risk of migraine.

Indexed as

Body CompositionBody WeightHumansMigraine DisordersRisk

Identifiers

PMID28404807
PMCPMC5419981
OpenAlexW2605835646

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.