Evidence map›Paper›PMID 28404800›Full record

ArticleNeurology2017

Racial differences in statin adherence following hospital discharge for ischemic stroke.

Karen C Albright, Hong Zhao, Justin Blackburn, Nita A Limdi, T Mark Beasley, George Howard, Vera Bittner, Virginia J Howard, Paul Muntner

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Interventions to Reduce Ethnic and Racial Disparities in Dyslipidemia Management.Current treatment options in cardiovascular medicine · 2019
    Review
  10. Article
  11. Issues in the Use of Human Tissues to Support Precision Medicine.Journal of health care for the poor and underserved · 2019
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Karen C AlbrightFrom the Geriatric Research, Education and Clinical Center (GRECC) (K.C.A.), Birmingham VA Medical Center; and the Departments of Epidemiology (K.C.A., H.Z., N.A.L., V.J.H., P.M.), Health Care Organization and Policy (J.B.), Neurology (N.A.L.), and Biostatistics (T.M.B., G.H.), and the Division of Cardiovascular Disease, Department of Medicine (V.B.), University of Alabama at Birmingham. kca@uab.edu.
Hong ZhaoFrom the Geriatric Research, Education and Clinical Center (GRECC) (K.C.A.), Birmingham VA Medical Center; and the Departments of Epidemiology (K.C.A., H.Z., N.A.L., V.J.H., P.M.), Health Care Organization and Policy (J.B.), Neurology (N.A.L.), and Biostatistics (T.M.B., G.H.), and the Division of Cardiovascular Disease, Department of Medicine (V.B.), University of Alabama at Birmingham.
Justin BlackburnFrom the Geriatric Research, Education and Clinical Center (GRECC) (K.C.A.), Birmingham VA Medical Center; and the Departments of Epidemiology (K.C.A., H.Z., N.A.L., V.J.H., P.M.), Health Care Organization and Policy (J.B.), Neurology (N.A.L.), and Biostatistics (T.M.B., G.H.), and the Division of Cardiovascular Disease, Department of Medicine (V.B.), University of Alabama at Birmingham.
Nita A LimdiFrom the Geriatric Research, Education and Clinical Center (GRECC) (K.C.A.), Birmingham VA Medical Center; and the Departments of Epidemiology (K.C.A., H.Z., N.A.L., V.J.H., P.M.), Health Care Organization and Policy (J.B.), Neurology (N.A.L.), and Biostatistics (T.M.B., G.H.), and the Division of Cardiovascular Disease, Department of Medicine (V.B.), University of Alabama at Birmingham.
T Mark BeasleyFrom the Geriatric Research, Education and Clinical Center (GRECC) (K.C.A.), Birmingham VA Medical Center; and the Departments of Epidemiology (K.C.A., H.Z., N.A.L., V.J.H., P.M.), Health Care Organization and Policy (J.B.), Neurology (N.A.L.), and Biostatistics (T.M.B., G.H.), and the Division of Cardiovascular Disease, Department of Medicine (V.B.), University of Alabama at Birmingham.
George HowardFrom the Geriatric Research, Education and Clinical Center (GRECC) (K.C.A.), Birmingham VA Medical Center; and the Departments of Epidemiology (K.C.A., H.Z., N.A.L., V.J.H., P.M.), Health Care Organization and Policy (J.B.), Neurology (N.A.L.), and Biostatistics (T.M.B., G.H.), and the Division of Cardiovascular Disease, Department of Medicine (V.B.), University of Alabama at Birmingham.
Vera BittnerFrom the Geriatric Research, Education and Clinical Center (GRECC) (K.C.A.), Birmingham VA Medical Center; and the Departments of Epidemiology (K.C.A., H.Z., N.A.L., V.J.H., P.M.), Health Care Organization and Policy (J.B.), Neurology (N.A.L.), and Biostatistics (T.M.B., G.H.), and the Division of Cardiovascular Disease, Department of Medicine (V.B.), University of Alabama at Birmingham.
Virginia J HowardFrom the Geriatric Research, Education and Clinical Center (GRECC) (K.C.A.), Birmingham VA Medical Center; and the Departments of Epidemiology (K.C.A., H.Z., N.A.L., V.J.H., P.M.), Health Care Organization and Policy (J.B.), Neurology (N.A.L.), and Biostatistics (T.M.B., G.H.), and the Division of Cardiovascular Disease, Department of Medicine (V.B.), University of Alabama at Birmingham.
Paul MuntnerFrom the Geriatric Research, Education and Clinical Center (GRECC) (K.C.A.), Birmingham VA Medical Center; and the Departments of Epidemiology (K.C.A., H.Z., N.A.L., V.J.H., P.M.), Health Care Organization and Policy (J.B.), Neurology (N.A.L.), and Biostatistics (T.M.B., G.H.), and the Division of Cardiovascular Disease, Department of Medicine (V.B.), University of Alabama at Birmingham.

Funding

University of Alabama at Birmingham's Diabetes Research CenterP30DK079626 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BARBARA A GOWER · 2013 to 2026
$19.5M
Patient Oriented Research in Personalized Antithrombotic TherapyK24HL133373 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI LIMDI, NITA A · 2016 to 2025
$1.2M
NHLBI NIH HHS K24 HL133373NIDDK NIH HHS P30 DK079626
6 · The paper itself

Abstract

objectiveTo compare nonadherence to statins in older black and white adults following an ischemic stroke.

methodsWe studied black and white adults ≥66 years of age with Medicare fee-for-service insurance coverage hospitalized for ischemic stroke from 2007 to 2012 who filled a statin prescription within 30 days following discharge. Nonadherence was defined as a proportion of days covered <80% in the 365 days following hospital discharge. In addition, we evaluated factors associated with nonadherence for white and black participants separately.

resultsOverall 2,763 beneficiaries met the inclusion criteria (13.5% black). Black adults were more likely than white adults to be nonadherent (49.7% vs 41.5%) even after adjustment for demographics, receipt of a low-income subsidy, and baseline comorbidities (adjusted relative risk [RR] 1.14, 95% confidence interval [CI] 1.01-1.29). Among white adults, receipt of a low-income subsidy (adjusted RR 1.13, 95% CI 1.02-1.26), history of coronary heart disease (adjusted RR 1.15, 95% CI 1.01-1.30), and discharge directly home following stroke hospitalization (adjusted RR 1.26, 95% CI 1.10-1.44) were associated with a higher risk of nonadherence. Among black adults, a 1-unit increase in the Charlson comorbidity index (adjusted RR 1.04, 95% CI 1.01-1.09), history of carotid artery disease (adjusted RR 2.38, 95% CI 1.08-5.25), and hospitalization during the 365 days prior to the index stroke (adjusted RR 1.34, 95% CI 1.01-1.78) were associated with nonadherence.

conclusionsCompared with white adults, black adults were more likely to be nonadherent to statins following hospitalization for ischemic stroke.

Indexed as

AgedBlack or African AmericanBrain IschemiaCarotid Artery DiseasesComorbidityCoronary DiseaseFemaleHumansHydroxymethylglutaryl-CoA Reductase InhibitorsMaleMedicareMedication AdherencePatient DischargeRetrospective StudiesRisk FactorsSelf ReportHydroxymethylglutaryl-CoA Reductase Inhibitors

Identifiers

PMID28404800
PMCPMC5419984

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.