Evidence map›Paper›PMID 28404671›Full record

ReviewJournal of clinical microbiology2017

Update on Antimicrobial Resistance in Clostridium difficile: Resistance Mechanisms and Antimicrobial Susceptibility Testing.

Zhong Peng, Dazhi Jin, Hyeun Bum Kim, Charles W Stratton, Bin Wu, Yi-Wei Tang, Xingmin Sun

Abstract readReview
In one paragraph

Review in Journal of clinical microbiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
144citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

144 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. The prevalence and molecular epidemiology ofEmerging microbes & infections · 2026
    Observational
  6. Article
  7. Article
  8. Healthcare-associated infections and antimicrobial resistance in Canadian acute care hospitals, 2020-2024.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2026
    Article
  9. Article
  10. Article
  11. Article
  12. Variety ofGerms · 2026
    Article
  13. Article
  14. Pangenome-GWAS analysis ofCanadian journal of microbiology · 2026
    Article
  15. Article
  16. Clinical and molecular epidemiology ofFrontiers in microbiology · 2026
    Article
  17. Lipidomics, Microbiota, and IntestinalInternational journal of molecular sciences · 2025
    Review
  18. Mobilome of Environmental Isolates ofAntibiotics (Basel, Switzerland) · 2025
    Article
  19. Healthcare-associated infections and antimicrobial resistance in Canadian acute care hospitals, 2019-2023.Canada communicable disease report = Releve des maladies transmissibles au Canada · 2025
    Article
  20. Article

84 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zhong PengDepartment of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA.
Dazhi JinDepartment of Microbiology, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou, Zhejiang, China.ORCID 0000-0001-7738-1778
Hyeun Bum KimDepartment of Animal Resources Science, Dankook University, Cheonan, South Korea.
Charles W StrattonDepartment of Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Bin WuState Key Laboratory of Agricultural Microbiology, College of Veterinary Medicine, Huazhong Agricultural University, Wuhan, Hubei, China.
Yi-Wei TangDepartment of Laboratory Medicine, Memorial Sloan Kettering Cancer Center, New York, New York, USA tangy@mskcc.org sun5@health.usf.edu.ORCID 0000-0003-4888-6771
Xingmin SunDepartment of Molecular Medicine, Morsani College of Medicine, University of South Florida, Tampa, Florida, USA tangy@mskcc.org sun5@health.usf.edu.

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
Signaling pathway of TNF-alpha production and Clostridium difficile infection (CDK01DK092352 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI SUN, XINGMIN · 2012 to 2016
$470k
Multivalent Bacillus mucosal vaccines against Clostridium difficile infectionR21AI113470 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI SUN, XINGMIN · 2015 to 2016
$438k
NCI NIH HHS P30 CA008748NIAID NIH HHS R21 AI113470NIDDK NIH HHS K01 DK092352
6 · The paper itself

Abstract

Oral antibiotics such as metronidazole, vancomycin and fidaxomicin are therapies of choice for

Indexed as

Drug Resistance, BacterialAnti-Bacterial AgentsClostridioides difficileGenes, BacterialHumansMicrobial Sensitivity TestsAnti-Bacterial AgentsantibioticsbiofilmClostridium difficiledrug resistancetesting

Identifiers

PMID28404671
PMCPMC5483901

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.