Evidence map›Paper›PMID 28404606›Full record

ReviewEMBO reports2017

Local translation in neuronal compartments: how local is local?

Vidhya Rangaraju, Susanne Tom Dieck, Erin M Schuman

Abstract readReview
In one paragraph

Review in EMBO reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 107 papers.

0numbers the graph read from it
0cells of the map it votes in
107citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

107 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. From development to disease: the neuronal role of hnRNPs through the lens ofFrontiers in cell and developmental biology · 2026
    Review
  9. Article
  10. Self-renewal of neuronal mitochondria through asymmetric division.bioRxiv : the preprint server for biology · 2025
    Article
  11. Article
  12. Review
  13. Review
  14. Article
  15. Article
  16. A practical guide to sequencing in neuropsychiatric research.NPP - digital psychiatry and neuroscience · 2025
    Review
  17. Article
  18. Article
  19. Article
  20. Article

47 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Vidhya RangarajuMax Planck Institute for Brain Research, Frankfurt am Main, Germany vidhya.rangaraju@brain.mpg.de.ORCID 0000-0002-6716-4312
Susanne Tom DieckMax Planck Institute for Brain Research, Frankfurt am Main, Germany.
Erin M SchumanMax Planck Institute for Brain Research, Frankfurt am Main, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Efficient neuronal function depends on the continued modulation of the local neuronal proteome. Local protein synthesis plays a central role in tuning the neuronal proteome at specific neuronal regions. Various aspects of translation such as the localization of translational machinery, spatial spread of the newly translated proteins, and their site of action are carried out in specialized neuronal subcompartments to result in a localized functional outcome. In this review, we focus on the various aspects of these local translation compartments such as size, biochemical and organelle composition, structural boundaries, and temporal dynamics. We also discuss the apparent absence of definitive components of translation in these local compartments and the emerging state-of-the-art tools that could help dissecting these conundrums in greater detail in the future.

Indexed as

Neuronal PlasticityProtein BiosynthesisAnimalsDendritesNeuronsOrganellesProteomeRNA, MessengerProteomeRNA, Messengercompartmentslocal translationnascent proteinplasticityspatial spread

Identifiers

PMID28404606
PMCPMC5412868

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.