Evidence map›Paper›PMID 28404574›Full record

ArticleClinical and vaccine immunology : CVI2017

Parasitic Infections in Pregnancy Decrease Placental Transfer of Antipneumococcus Antibodies.

Noah D McKittrick, David M Vu, Indu Malhotra, Charles H King, Francis Mutuku, A Desiree LaBeaud

Open access · diamondAbstract read
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.

  1. Pooled it
  2. Article
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  5. Review
  6. Article
  7. HLA antibody repertoire in infants suggests selectivity in transplacental crossing.American journal of reproductive immunology (New York, N.Y. : 1989) · 2020
    Article
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Noah D McKittrickDivision of Infectious Diseases, Department of Medicine, Stanford University School of Medicine, Stanford, California, USA noahmck@stanford.edu.ORCID http://orcid.org/0000-0001-6277-2733
David M VuDivision of Infectious Diseases, Department of Pediatrics, Lucille Packard Children's Hospital at Stanford School of Medicine, Stanford, California, USA.
Indu MalhotraCenter for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Charles H KingCenter for Global Health and Diseases, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.
Francis MutukuDepartment of Environment and Health Sciences, Technical University of Mombasa, Mombasa, Kenya.
A Desiree LaBeaudDivision of Infectious Diseases, Department of Pediatrics, Lucille Packard Children's Hospital at Stanford School of Medicine, Stanford, California, USA.
Center for Global Health · USLucile Packard Children's Hospital · USStanford University · USTechnical University of Mombasa · KE

Funding

Spectrum Stanford Center for clinical and Translational Research and EducationUL1TR001085 · NCATS · STANFORD UNIVERSITY · PI CULLEN, MARK RICHARD, GREENBERG, HARRY BERNARD · 2013 to 2017
$37.1M
Spectrum Stanford Center for clinical and Translational Research and EducationKL2TR001083 · NCATS · STANFORD UNIVERSITY · PI CULLEN, MARK RICHARD, GREENBERG, HARRY BERNARD · 2013 to 2017
$4.9M
NCATS NIH HHS KL2 TR001083NCATS NIH HHS UL1 TR001085NIAID NIH HHS L40 AI057605
6 · The paper itself

Abstract

Many factors can influence maternal placental antibody transfer to the fetus, which confers important immune protection to the newborn infant. However, little is known about the effect of maternal parasitic infection on placental antibody transfer. To investigate this, we selected from a parent study of 576 pregnant Kenyan women four groups of women with term deliveries (≥37 weeks), including uninfected women (

Indexed as

Biological TransportMaternal-Fetal ExchangeAdultAntibodies, BacterialCohort StudiesFemaleFetal BloodFollow-Up StudiesHumansImmunoglobulin GInfant, NewbornKenyaMaleParasitic DiseasesPlacentaPregnancyAntibodies, BacterialImmunoglobulin Ghumoral immunityparasitesplacental antibody transferpregnancy

Identifiers

PMID28404574
PMCPMC5461374
OpenAlexW2606115039

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.