Evidence map›Paper›PMID 28404573›Full record

ArticleClinical and vaccine immunology : CVI2017

Cytomegalovirus Virions Shed in Urine Have a Reversible Block to Epithelial Cell Entry and Are Highly Resistant to Antibody Neutralization.

Xiaohong Cui, Stuart P Adler, Mark R Schleiss, Ravit Arav-Boger, Gail J Demmler Harrison, Michael A McVoy

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Clinical and vaccine immunology : CVI, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. A viral glycoprotein targets IgGEMBO molecular medicine · 2026
    Article
  2. Article
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  7. Article
  8. A Native Human Monoclonal Antibody Targeting HCMV gB (AD-2 Site I).International journal of molecular sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Xiaohong CuiVirginia Commonwealth University, Richmond, Virginia, USA.
Stuart P AdlerCMV Research Foundation, Richmond, Virginia, USA.
Mark R SchleissCenter for Infectious Diseases and Microbiology Translational Research, Division of Pediatric Infectious Diseases, Minneapolis, Minnesota, USA.
Ravit Arav-BogerDivision of Pediatric Infectious Diseases, Johns Hopkins Hospital, Baltimore, Maryland, USA.ORCID http://orcid.org/0000-0002-5363-167X
Gail J Demmler HarrisonBaylor College of Medicine, Houston, Texas, USA.
Michael A McVoyVirginia Commonwealth University, Richmond, Virginia, USA michael.mcvoy@vcuhealth.org.
Virginia Commonwealth University · USBaylor College of Medicine · USJohns Hopkins Hospital · USOrthopaedic Research of Virginia · US

Funding

Preclinical development of human CMV vaccinesR01AI088750 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI MCVOY, MICHAEL A · 2010 to 2014
$3.9M
Optimized Vaccines Against Congenital Infection and Maternal Reinfection with CMVR01HD079918 · NICHD · UNIVERSITY OF MINNESOTA · PI SCHLEISS, MARK R. · 2015 to 2019
$1.6M
Ability of CMV Vaccines to Induce Antibodies that Block Endocytic EntryR21AI073615 · NIAID · VIRGINIA COMMONWEALTH UNIVERSITY · PI MCVOY, MICHAEL A · 2008 to 2009
$389k
NIAID NIH HHS R01 AI088750NIAID NIH HHS R21 AI073615NICHD NIH HHS R01 HD079918
6 · The paper itself

Abstract

Cytomegalovirus (CMV) causes sensorineural hearing loss and developmental disabilities in newborns when infections are acquired

Indexed as

Viral TropismVirus SheddingAntibodies, NeutralizingAntibodies, ViralCytomegalovirusCytomegalovirus InfectionsEpithelial CellsFibroblastsHumansInfant, NewbornVirionVirus InternalizationAntibodies, NeutralizingAntibodies, Viralcongenital infectioncytomegalovirusneutralizing antibodiesvaccine

Identifiers

PMID28404573
PMCPMC5461377
OpenAlexW2607097647

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.