ArticleItalian journal of pediatrics2017
Lung structure and function similarities between primary ciliary dyskinesia and mild cystic fibrosis: a pilot study.
Article in Italian journal of pediatrics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- Pulmonary MRI in Newborns and Children.Journal of magnetic resonance imaging : JMRI · 2025Review
- Lung ultrasound in children with primary ciliary dyskinesia or cystic fibrosis.Pediatric pulmonology · 2024Article
- Lung function from school age to adulthood in primary ciliary dyskinesia.The European respiratory journal · 2022Article
- Quantitative analysis of changes in lung density by dynamic chest radiography in association with CT values: a virtual imaging study and initial clinical corroboration.Radiological physics and technology · 2022Article
- Lower airway clinical outcome measures for use in primary ciliary dyskinesia research: a scoping review.ERJ open research · 2021Article
- Comparison of Multiple Breath Washout and Spirometry in Children with Primary Ciliary Dyskinesia and Cystic Fibrosis and Healthy Controls.Annals of the American Thoracic Society · 2020Observational
- Prevalence and course of disease after lung resection in primary ciliary dyskinesia: a cohort & nested case-control study.Respiratory research · 2019Article
- Thoracic calcifications on magnetic resonance imaging: correlations with computed tomography.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2019Article
- Primary Ciliary Dyskinesia: Longitudinal Study of Lung Disease by Ultrastructure Defect and Genotype.American journal of respiratory and critical care medicine · 2019Observational
- Imaging Lung Function Abnormalities in Primary Ciliary Dyskinesia Using Hyperpolarized Gas Ventilation MRI.Annals of the American Thoracic Society · 2018Article
- Bronchiectasis in PCD looks different to CF on CT scan.Multidisciplinary respiratory medicine · 2018Article
- A pediatric disease to keep in mind: diagnostic tools and management of bronchiectasis in pediatric age.Italian journal of pediatrics · 2017Review
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPrimary ciliary dyskinesia (PCD) and cystic fibrosis (CF) are increasingly compared. There are no chest magnetic resonance imaging (MRI) comparative studies of PCD and CF. We assessed clinical, functional, microbiological and MRI findings in PCD and mild CF patients in order to evaluate different expression of lung disease.
methodsTwenty PCD (15.1 years) and 20 CF subjects with mild respiratory impairment (16 years, 70% with pancreatic insufficiency) underwent MRI, spirometry, and sputum cultures when clinically stable. MRI was scored using the modified Helbich system.
resultsPCD was diagnosed later than CF (9.9 versus 0.6 years, p = 0.03), despite earlier symptoms (0.1 versus 0.6 years, p = 0.02). In the year preceding the study, patients from both groups underwent two systemic antibiotic courses (p = 0.48). MRI total scores were 11.6 ± 0.7 and 9.1 ± 1 in PCD and CF, respectively. FEV
conclusionsMRI is a valuable radiation-free tool for comparative PCD and CF lung disease assessment. Patients with PCD may exhibit similar MRI and lung function changes as CF subjects with mild pulmonary disease. Delay in PCD diagnosis is unlikely the only determinant of similarities.
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