ArticleBMC genomics2017
Characterization of genome-wide segmental duplications reveals a common genomic feature of association with immunity among domestic animals.
Article in BMC genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
15 citing papers in PubMed, 27 citations in OpenAlex.
- Quantifying the Influence of Genetic Context on Duplicated Mammalian Genes.Molecular biology and evolution · 2026Article
- Quantifying the influence of genetic context on duplicated mammalian genes.bioRxiv : the preprint server for biology · 2025Article
- Amniotes co-opt intrinsic genetic instability to protect germ-line genome integrity.Nature communications · 2023Article
- Article
- Genomic scans for selective sweeps through haplotype homozygosity and allelic fixation in 14 indigenous sheep breeds from Middle East and South Asia.Scientific reports · 2021Article
- Genome-Wide Assessment Characteristics of Genes Overlapping Copy Number Variation Regions in Duroc Purebred Population.Frontiers in genetics · 2021Article
- Article
- Article
- Functional and population genetic features of copy number variations in two dairy cattle populations.BMC genomics · 2020Article
- Genome-Wide Detection of CNVs and Association With Body Weight in Sheep Based on 600K SNP Arrays.Frontiers in genetics · 2020Article
- Gene Fusions Derived by Transcriptional Readthrough are Driven by Segmental Duplication in Human.Genome biology and evolution · 2019Article
- Improving Illumina assemblies with Hi-C and long reads: An example with the North African dromedary.Molecular ecology resources · 2019Article
- Evolutionary history of the human multigene families reveals widespread gene duplications throughout the history of animals.BMC evolutionary biology · 2019Article
- A large interactive visual database of copy number variants discovered in taurine cattle.GigaScience · 2019Article
- Mammalian Annotation Database for improved annotation and functional classification of Omics datasets from less well-annotated organisms.Database : the journal of biological databases and curation · 2019Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSegmental duplications (SDs) commonly exist in plant and animal genomes, playing crucial roles in genomic rearrangement, gene innovation and the formation of copy number variants. However, they have received little attention in most livestock species.
resultsAiming at characterizing SDs across the genomes of diverse livestock species, we mapped genome-wide SDs of horse, rabbit, goat, sheep and chicken, and also enhanced the existing SD maps of cattle and pig genomes based on the most updated genome assemblies. We adopted two different detection strategies, whole genome analysis comparison and whole genome shotgun sequence detection, to pursue more convincing findings. Accordingly we identified SDs for each species with the length of from 21.7 Mb to 164.1 Mb, and 807 to 4,560 genes were harboured within the SD regions across different species. More interestingly, many of these SD-related genes were involved in the process of immunity and response to external stimuli. We also found the existence of 59 common genes within SD regions in all studied species except goat. These common genes mainly consisted of both UDP glucuronosyltransferase and Interferon alpha families, implying the connection between SDs and the evolution of these gene families.
conclusionsOur findings provide insights into livestock genome evolution and offer rich genomic sources for livestock genomic research.
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