ArticlePloS one2017
Improving specificity of Bordetella pertussis detection using a four target real-time PCR.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Article
- Critical pertussis infection in the paediatric intensive care unit: A case series in an outbreak.The Southern African journal of critical care : the official journal of the Critical Care Society · 2025Article
- Bordetella pertussis DNA detected in a tracheostomized child blood before seroconversion.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021Article
- Establishment and application of a multiple cross displacement amplification combined with nanoparticles-based biosensor method for the detection of Bordetella pertussis.BMC microbiology · 2020Article
- A qPCR assay for Bordetella pertussis cells that enumerates both live and dead bacteria.PloS one · 2020Article
- Article
- A low-cost microfluidic platform for rapid and instrument-free detection of whooping cough.Analytica chimica acta · 2019Article
- Multicenter Clinical Evaluation of the Automated AriesJournal of clinical microbiology · 2019Article
- Validation and Implementation of a Diagnostic Algorithm for DNA Detection of Bordetella pertussis, B. parapertussis, and B. holmesii in a Pediatric Referral Hospital in Barcelona, Spain.Journal of clinical microbiology · 2019Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The incidence of whooping cough, a contagious respiratory disease caused by Bordetella pertussis, is on the rise despite existing vaccination programmes. Similar, though usually milder, respiratory symptoms may be caused by other members of the Bordetella genus: B. parapertussis, B. holmesii, and B. bronchiseptica. Pertussis diagnosis is mostly done using PCR, but the use of multiple targets is necessary in order to differentiate the different Bordetella spp. with sufficient sensitivity and specificity. In this study we evaluate a multiplex PCR assay for the differentiation of B. pertussis from other Bordetella spp., using the targets IS481, IS1001, IS1002, and recA. Moreover, we retrospectively explore the epidemiology of Bordetella spp. infections in Belgium, using the aforementioned assay over a three-year period, from 2013 until 2015.
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