ArticlePloS one2017
A protocol for identifying suitable biomarkers to assess fish health: A systematic review.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
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Who cites it
34 citing papers in PubMed.
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- Fish in focus: Navigating organ damage assessment through analytical avenues - A comprehensive review.Toxicology reports · 2024Review
- Assessment of biochemical biomarkers and environmental stress indicators in some freshwater fish.Environmental geochemistry and health · 2024Article
- Biomarker responses in Danio rerio following an acute exposure (96 h) to e-waste leachate.Ecotoxicology (London, England) · 2024Article
- Inclusion Effect of Various Levels of Jack Mackerel Meal in Olive Flounder (Animals : an open access journal from MDPI · 2024Article
- Discovery of mass spectral peak markers and protein biomarkers in fish muscle exudates for rapid and precise recognition of fish species via magnetic beads (MBs) and mass spectrometry.Food chemistry: X · 2024Article
- Immunological and molecular diagnostic techniques in fish health: present and future prospectus.Molecular biology reports · 2024Review
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- Occurrence of pesticide residues and associated ecological risks assessment in water and sediment from selected dams in northern Ghana.PloS one · 2024Article
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- Transgenerational exposure to ocean acidification impacts the hepatic transcriptome of European sea bass (Dicentrarchus labrax).BMC genomics · 2023Article
- Physiological Benefits of Dietary Lysophospholipid Supplementation in a Marine Fish Model: Deep Analyses of Modes of Action.Animals : an open access journal from MDPI · 2023Article
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBiomarkers have been used extensively to provide the connection between external levels of contaminant exposure, internal levels of tissue contamination, and early adverse effects in organisms.
objectivesTo present a three-step protocol for identifying suitable biomarkers to assess fish health in coastal and marine ecosystems, using Gladstone Harbour (Australia) as a case study.
methodsPrior to applying our protocol, clear working definitions for biomarkers were developed to ensure consistency with the global literature on fish health assessment. First, contaminants of concern were identified based on the presence of point and diffuse sources of pollution and available monitoring data for the ecosystem of interest. Second, suitable fish species were identified using fisheries dependent and independent data, and prioritised based on potential pathways of exposure to the contaminants of concern. Finally, a systematic and critical literature review was conducted on the use of biomarkers to assess the health of fish exposed to the contaminants of concern. RESULTS/DISCUSSION: We present clear working definitions for bioaccumulation markers, biomarkers of exposure, biomarkers of effect and biomarkers of susceptibility. Based on emission and concentration information, seven metals were identified as contaminants of concern for Gladstone Harbour. Twenty out of 232 fish species were abundant enough to be potentially suitable for biomarker studies; five of these were prioritised based on potential pathways of exposure and susceptibility to metals. The literature search on biomarkers yielded 5,035 articles, of which 151met the inclusion criteria. Based on our review, the most suitable biomarkers include bioaccumulation markers, biomarkers of exposure (CYP1A, EROD, SOD, LPOX, HSP, MT, DNA strand breaks, micronuclei, apoptosis), and biomarkers of effect (histopathology, TAG:ST).
conclusionOur protocol outlines a clear pathway to identify suitable biomarkers to assess fish health in coastal and marine ecosystems, which can be applied to biomarker studies in aquatic ecosystems around the world.
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