ArticlePLoS computational biology2017
Increased decision thresholds enhance information gathering performance in juvenile Obsessive-Compulsive Disorder (OCD).
Article in PLoS computational biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
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Who cites it
38 citing papers in PubMed.
- Beta-Blocker Propranolol Modulates Decision Urgency During Sequential Information Gathering.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Trial
- cpm: A python library for theory-driven modelling in computational psychiatry.PLoS computational biology · 2026Article
- Obsessive-compulsive disorders (OCD) and job performance among Iranian healthcare workers.BMC primary care · 2026Article
- Indecision and recency-weighted evidence integration in non-clinical and clinical settings.Nature human behaviour · 2026Article
- Structural synaptogenesis superior to functional modulation in a pruning-based recurrent network model of OCD.Frontiers in computational neuroscience · 2026Article
- The metacognitive paradox of OCD: confidence is globally reduced but shows increased sensitivity to local evidence.Research square · 2025Article
- Addressing Altered Anticipation as a Transdiagnostic Target Through Computational Psychiatry.Biological psychiatry. Cognitive neuroscience and neuroimaging · 2025Review
- Active information sampling in health and disease.Neuroscience and biobehavioral reviews · 2025Review
- A neural code supporting prospective probabilistic reasoning for instrumental information demand in humans.Communications biology · 2024Article
- Compulsive avoidance in youths and adults with OCD: an aversive pavlovian-to-instrumental transfer study.Translational psychiatry · 2024Article
- Transdiagnostic Anxiety-Related Increases in Information Sampling are Associated With Altered Valuation.Computational psychiatry (Cambridge, Mass.) · 2024Article
- Boosting Serotonin Increases Information Gathering by Reducing Subjective Cognitive Costs.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Disorder-specific cingulo-opercular network hyperconnectivity in pediatric OCD relative to pediatric anxiety.Psychological medicine · 2023Article
- Atypical action updating in a dynamic environment associated with adolescent obsessive-compulsive disorder.Journal of child psychology and psychiatry, and allied disciplines · 2022Article
- The promise of a model-based psychiatry: building computational models of mental ill health.The Lancet. Digital health · 2022Review
- Controllability boosts neural and cognitive signatures of changes-of-mind in uncertain environments.eLife · 2022Article
- Article
- Anxiety increases information-seeking in response to large changes.Scientific reports · 2022Article
- The effect of apathy and compulsivity on planning and stopping in sequential decision-making.PLoS biology · 2022Article
- Accumulation of evidence during decision making in OCD patients.Frontiers in psychiatry · 2022Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with obsessive-compulsive disorder (OCD) can be described as cautious and hesitant, manifesting an excessive indecisiveness that hinders efficient decision making. However, excess caution in decision making may also lead to better performance in specific situations where the cost of extended deliberation is small. We compared 16 juvenile OCD patients with 16 matched healthy controls whilst they performed a sequential information gathering task under different external cost conditions. We found that patients with OCD outperformed healthy controls, winning significantly more points. The groups also differed in the number of draws required prior to committing to a decision, but not in decision accuracy. A novel Bayesian computational model revealed that subjective sampling costs arose as a non-linear function of sampling, closely resembling an escalating urgency signal. Group difference in performance was best explained by a later emergence of these subjective costs in the OCD group, also evident in an increased decision threshold. Our findings present a novel computational model and suggest that enhanced information gathering in OCD can be accounted for by a higher decision threshold arising out of an altered perception of costs that, in some specific contexts, may be advantageous.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.