ArticleMedicine2017
Low serum levels of uric acid and albumin in patients with Guillain-Barre syndrome.
Article in Medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 26 citations in OpenAlex.
- Low uric acid predicts severe outcomes in neuronal surface antibody-mediated autoimmune encephalitis.BMC neurology · 2026Article
- A study on the role of serum uric acid in differentiating acute inflammatory demyelinating polyneuropathy from acute-onset chronic inflammatory demyelinating polyneuropathy.European journal of neurology · 2024Article
- Clinical features of patients with MOG-IgG associated disorders and analysis of the relationship between fibrinogen-to-albumin ratio and the severity at disease onset.Frontiers in neurology · 2023Article
- Association of serum uric acid levels with COVID-19 severity.BMC endocrine disorders · 2021Article
- Determinants of serum uric acid levels in an adult general population: results from the Moli-sani Study.Clinical rheumatology · 2021Article
- Roma Ethnicity and Sex-Specific Associations of Serum Uric Acid with Cardiometabolic and Hepatorenal Health Factors in Eastern Slovakian Population: The HepaMeta Study.International journal of environmental research and public health · 2020Article
- Low Antioxidant Status of Serum Uric Acid, Bilirubin, Albumin, and Creatinine in Patients With Benign Paroxysmal Positional Vertigo.Frontiers in neurology · 2020Article
- Exercise-Related Oxidative Stress as Mechanism to Fight Physical Dysfunction in Neuromuscular Disorders.Frontiers in physiology · 2020Review
- Increased Cerebrospinal Fluid Uric Acid Levels in Guillain-Barré Syndrome.Frontiers in neurology · 2020Article
- Clinical characteristics of rheumatoid arthritis patients with peripheral neuropathy and potential related risk factors.Clinical rheumatology · 2019Observational
- Pain during the acute phase of Guillain-Barré syndrome.Medicine · 2018Observational
- Erratum: Low serum levels of uric acid and albumin in patients with GuillainBarre syndrome: Erratum.Medicine · 2017Article
Corrections and comments
- Erratum issued
Authors and funding
25 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Free radical toxicity due to poorly maintained cellular redox levels is crucial events that have been associated with the pathogenesis of Guillain-Barre syndrome (GBS) patients. Uric acid (UA) and albumin correlate with oxidative stress in some degree. We aimed to evaluate the relationship between GBS and serum levels of UA and albumin in the present study.The serum levels of UA and albumin were determined in 203 individuals including 88 patients with GBS and 153 healthy controls (HC).We found that serum levels of UA and albumin in patients with GBS were significantly lower than those in HC group. Besides, similar phenomenon was observed when the male and female subgroups were estimated, respectively. Additionally, we found that there is no statistic difference among subgroups of GBS regarding UA and albumin. The univariate analysis revealed that both the high UA and high albumin were protective factors for patients with GBS (odds ratio [OR] 0.140; 95% confidence interval [CI]: 0.074-0.264; P < .001 and OR 0.016; 95% CI: 0.006-0.038; P < .001, respectively). It was further confirmed by the multivariable logistic regression analysis after adjusting for other potential confounding factors (OR 0.168; 95% CI: 0.055-0.514; P = .002 and OR 0.027; 95% CI: 0.011-0.071; P < .001, respectively).In conclusion, we found that patients with GBS had significantly low serum UA and albumin levels. Moreover, we demonstrated that both the high UA and high albumin were protective factors for patients with GBS.
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